Application of Chinese medicinal composition in preparing medicament for treating facial spasm

A technology for hemifacial spasm and composition, which is applied in the field of application of traditional Chinese medicine composition in the preparation of medicines for treating hemifacial spasm, and can solve problems such as hindering social interaction and affecting appearance

Inactive Publication Date: 2008-09-24
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this disease is not life-threatening, it affects appearance and hinders social interaction, which makes patients feel very troubled

Method used

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  • Application of Chinese medicinal composition in preparing medicament for treating facial spasm

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] a) The raw material drug formula is:

[0054] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0055] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 19.8g

[0056] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g;

[0057] b) Crushing process of medicinal materials:

[0058] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0059] c) Extraction concentration and dr...

experiment example

[0066] 1 Materials and methods

[0067] 1.1 The clinical data were selected from 76 patients with hemifacial spasm who were treated in the Department of Neurology, Taihang Hospital, Taiyuan, from January 2006 to May 2006, and were randomly divided into treatment groups of 38 cases (14 females and 24 males). Aged 42.38±10.54 years old, disease course 5 months to 5 years, average 2 years 5 months; control group 38 cases (16 females, 22 males), average age 43.68±11.20 years old, disease course 6 months to 6 years, An average of 2 years and 6 months. There was no significant difference in baseline data between the two groups (P<0.05). All patients had no other focal signs of the nervous system except facial muscle spasm.

[0068] 1.2 Treatment method: The routine treatment group was given oral carbamazepine (produced by Shanghai Sanwei Pharmaceutical Co., Ltd., Shanghai Weiyao Zhunzi No. 002089, 1995) according to the routine treatment, 0.1g / time, 3 times a day. Based on the ca...

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Abstract

The invention discloses the application of a traditional Chinese medicine compound in preparing a drug for treating facial spasm. Clinical trials prove that the drug compound has the efficacies of Qi tonifying, channel clearing, blood stasis removing and spasmolysis and is applicable to the treatment of facial spasm patients.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular, the invention relates to an application of a traditional Chinese medicine composition in preparing a medicine for treating hemifacial spasm. Background technique [0002] Hemifacial spasm (HFS) is one of the more refractory diseases of the nervous system, mostly secondary to mouth and eye distortion, manifested as paroxysmal involuntary spasmodic twitching of one side of the facial muscles. Facial muscle spasm belongs to the category of "muscle urgency", "spasm syndrome" and "muscle embellishment" in traditional Chinese medicine. "On" said: "All winds and dizziness belong to the liver." Hemifacial spasm is caused by the flow of wind evil, and the external wind triggers the internal wind, resulting in poor meridians and stagnation of qi and blood. Although the disease is not life-threatening, it affects appearance and hinders social interaction, wh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61K9/08A61K9/10A61K9/20A61K9/48A61P25/02A61K35/64A61K35/62A61K31/045A61K35/646A61K35/648
Inventor 王天云
Owner HEBEI YILING MEDICINE INST
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