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New purpose of durio zibethinus L. shell extract

A technology of durian shell and extract, which is applied in application, food science, drug combination, etc., can solve the problem that intellectual property rights are not effectively protected

Inactive Publication Date: 2008-08-20
东莞市竟恒流通研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the existing patents on durian shells are only for the protection of food. There is little research on the application of durian shells in disease prevention, health function, medicine, health food and cosmetics, and the intellectual property rights have not been effectively protected.

Method used

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  • New purpose of durio zibethinus L. shell extract
  • New purpose of durio zibethinus L. shell extract
  • New purpose of durio zibethinus L. shell extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1. Preparation of durian husk extract: 100 grams of dried durian husks were pulverized using a pulverizer, and the finely powdered durian husks were recovered, and 4000 ml of water was added to heat-extract three times at 80° C. under pressure for 30 minutes. Then the extract is filtered through gauze, centrifuged at 10,000 rpm for 15 minutes, and the supernatant is recovered and freeze-dried. The above freeze-dried extract of durian husk with a recovery of about 28-32% was used in the following examples of the present invention.

Embodiment 2

[0023] Example 2. The effect of durian shell extract on improving alanine aminotransferase (ALT) disorder caused by restraint stress: the experiment used 6-week-old male Kunming mice purchased from the Guangdong Provincial Medical Experimental Animal Center, and the breeding temperature was 23 ± 2°C , the lighting time is 12 hours / day (7:00-19:00), and it is used for the experiment after one week of feeding. The mice were randomly divided into a blank control group, a restraint stress model group, and a positive drug control group (vitamin C 250 mg·kg -1 ), low-dose durian shell extract group (100mg·kg -1 ), medium dose durian shell extract group (300mg·kg -1 ), high-dose durian shell extract group (900mg·kg -1 ) and other administration groups, with 7 mice in each group, divided into 6 groups in total. Both the control group and the restraint load model group were intragastrically administered with the same volume of distilled water, once a day. On the 4th day, the mice in...

Embodiment 3

[0024] Embodiment three, durian shell extract promotes the mouse plasma malondialdehyde (MDA) abnormal recovery effect of restraint stress cause: experiment uses the 6 weeks old male Kunming mouse that Guangdong Provincial Medical Experimental Animal Center buys, raises temperature 23 ± 2°C, lighting time 12h / day (7:00-19:00), and feed for one week before experiment. The mice were randomly divided into a blank control group, a restraint stress model group, and a positive drug control group (vitamin C 250 mg·kg -1 ), low-dose durian shell extract group (100mg·kg -1 ), medium dose durian shell extract group (300mg·kg -1 ), high-dose durian shell extract group and other administration groups (900mg·kg -1 ), with 7 mice in each group, divided into 6 groups in total. Both the control group and the restraint load model group were intragastrically administered with the same volume of distilled water, once a day. On the 4th day, the mice in the model group, durian shell extract and...

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Abstract

The invention provides a medicine, a healthy food and a food additive with high safety and no side effect which are used to resist oxidation and stress, and eliminate a plurality of clinical symptoms due to stress load or body and mind fatigue, and are made from Durio zibethinus Murr shell or extract of Durio zibethinus Murr shell. Particularly, the invention provides the medicine, the healthy food, the food additive and a composition for improving body state, which is available for long-term use with high safety and no side effect; the medicine, the healthy food and the food additive are made from Durio zibethinus Murr shell or extract of Durio zibethinus Murr shell, and aim to improve levels of plasma Alanine amino ALT and MDA under stress load. Additionally, the invention proves that the medicine, the healthy food, the food additives and the composition made by extractions from Durio zibethinus Murr shell or extract of Durio zibethinus Murr shell can improve and relieve a plurality of clinical symptoms caused by oxidation resisting and anti-stress load.

Description

Technical field: [0001] The invention relates to the field of natural plant extraction and application. Background technique: [0002] Durian (Durio zibethinus Murr), also known as Shaozi, is the fruit of the long green tree durian in the family Kapokaceae, and is a tropical large fresh fruit with a strange flavor. Originally produced in India and the Malay Peninsula, it was first spread from the place of origin to the neighboring tropical countries in Southeast Asia and South Asia such as the Philippines, India, Sri Lanka and Indonesia. In recent years, a small amount of varieties have been introduced and cultivated in Guangxi and southern Yunnan. It is oval in shape and generally weighs about two kilograms. It has a woody hard shell on the outside and several rooms inside. Each room has three or four seeds the size of egg yolks. There are ten to fifteen seeds in total. The seeds are covered with a layer of ointment, which is the pulp. It is milky yellow, its fruit shape i...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P39/00A61P1/16A61P7/00A23L1/30A61K131/00A23L33/10A23L33/105
Inventor 冯锦和谢果栗原博
Owner 东莞市竟恒流通研究所
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