Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Micro-pore starch particles and producing method thereof

A technology of microporous starch and starch granules, which is applied in the field of microporous starch granules and its production, can solve problems such as difficulty in making preparations, insufficient drug loading, and insufficient loading, and achieve low price, ideal application prospects, and good The effect of loadability

Active Publication Date: 2012-03-21
ZHEJIANG UNIV OF TECH
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pore size of microporous starch is between 1 and 2 microns. As a carrier, its application is limited. The main disadvantage is that the loading capacity is not large enough. If it is used as a drug carrier, it is difficult to make an ideal preparation if the drug loading capacity is not enough.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Weigh 500g of cornstarch (produced by Shandong Zaozhuang Xiangyu Cornstarch Co., Ltd.), add 100g of water, seal and let stand for 48 hours to make the moisture even in the starch, then heat it at 90°C for 30 minutes, add 900g of water, and stir evenly. Add 225,000 units of amylase (produced by Jiangsu Wuxi Xuemei Enzyme Technology Co., Ltd.), control the pH to 5.5, and incubate and stir the reaction at 55°C for 6 hours. After the enzymatic hydrolysis reaction is completed, spray-dry to obtain microporous starch granules. Take a small amount of microporous starch granules and place them on the stage of the scanning electron microscope, put the stage into the gold plating instrument, spray carbon and gold-plate the sample, take out the stage after 2 hours and put it into the scanning electron microscope, observe the microporous starch The pore size of the micropores on the particle surface is compared with the scale, and the measured surface pore size ranges from 5 to 8 μm...

Embodiment 2

[0014] Weigh 1000g of potato starch (produced by Hebei Weichang Jiefeng Potato Starch Company), add 400g of water, seal and let stand for 24 hours to make the moisture even in the starch, then heat at 55°C for 120 minutes, add 3600g of water, stir evenly, add 650,000 units of amylase (manufactured by Jiangsu Wuxi Xuemei Enzyme Preparation Technology Co., Ltd.), controlled at pH 4.5, was incubated and stirred at 35°C for 2 hours. After the enzymatic hydrolysis reaction was completed, it was spray-dried to obtain microporous starch granules. Take a small amount of microporous starch granules and place them on the stage of the scanning electron microscope, put the stage into the gold plating instrument, spray carbon and gold-plate the sample, take out the stage after 2 hours and put it into the scanning electron microscope, observe the microporous starch The pore size of the micropores on the particle surface is compared with the scale, and the measured surface pore size ranges fr...

Embodiment 3

[0016] Weigh 800g of sweet potato starch (produced by Dongguan Huimei Starch Technology Co., Ltd.), add 240g of water, seal and let stand for 36 hours to make the moisture even in the starch, then heat it at 70°C for 60 minutes, add 2160g of water, and stir evenly. Add 480,000 units of amylase (produced by Jiangsu Wuxi Xuemei Enzyme Preparation Technology Co., Ltd.), control the pH to 5.0, and incubate and stir the reaction at 45°C for 3 hours. After the enzymatic hydrolysis reaction is completed, spray-dry to obtain microporous starch granules. Take a small amount of microporous starch granules and place them on the stage of the scanning electron microscope, put the stage into the gold plating instrument, spray carbon and gold-plate the sample, take out the stage after 2 hours and put it into the scanning electron microscope, observe the microporous starch The pore size of the micropores on the particle surface is compared with the scale, and the measured surface pore size ran...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
pore sizeaaaaaaaaaa
pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention provides a microporous starch grain with aperture over 5 mu m, and relatively high supporting capacity, and producing method thereof. The producing method includes: weight starch, charging water with a weight of 20-40% of the starch weight, sealed standing for 24-48 hours to make the water disperse uniformly in the starch, heating to keep temperature ranging from 55 to 90 DEG C. for30-120 minutes, charging water to make weight ratio of starch and water to 1:2 - 4, stirring uniformly, charging amylase according to a charging amount of 450-650 per grams of starch, stirring and reacting for 2-6 hours with pH ranging from 4.5 to 5.5, temperature ranging 35-55 DEG C., spray drying after completion of the reaction, aforementioned microporous starch grain is obtained. The inventive microporous starch grain has a surface aperture of 5-10 mu m, 3-10 times large than microporous starch grain prepared by conventional technology, thus has a better supporting property, and larger supporting capacity than products of conventional technology, which makes it has better effects than products of conventional technology when applied to fields of medicament preparation, food additive, pesticide and fertilizer as carrier.

Description

(1) Technical field [0001] The invention relates to a microporous starch granule and a production method thereof. (2) Background technology [0002] The starch is processed into starch granules with microporous surfaces. A large number of technical researches have been carried out at home and abroad. The microporous starch granules produced by the existing technology have a pore size of 1 to 2 microns on the surface of the starch granules. The starch granules produced by the two techniques are produced by enzymatic hydrolysis after ultrasonic treatment, or directly by enzymatic hydrolysis. The distribution of micropores on the surface of the starch granules produced by the two techniques is different, and the starch granules produced by direct enzymatic hydrolysis have fewer surface pores. The pore size of microporous starch is between 1 and 2 microns. As a carrier, its application is limited. The main disadvantage is that the loading capacity is not large enough. If it is u...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08L3/02C08J9/00C12S3/12
Inventor 钱俊青应雪肖
Owner ZHEJIANG UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com