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Method for extracting active component from cistanche salsa

An active ingredient, technology of Cistanche deserticola, applied in the field of Cistanche deserticola extract, can solve problems such as short process flow, and achieve the effects of short process flow, overcoming serious degradation loss and less dosage

Active Publication Date: 2008-07-09
SUN YAT SEN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention proposes a production method for extracting Cistanche extract rich in active ingredients echinacoside and verbascoside monomer compounds from fresh Cistanche sarcosides with high yield through the system integration technology, through the cell crushing process, The implementation of system integration technologies such as slurry extraction process, membrane separation process, high-temperature enzyme inactivation process, spray drying process, etc., the process flow is short, water is used as the solvent and the amount is very small, which meets the environmental protection requirements of energy saving and emission reduction, and can be realized within 15 to 60 minutes Complete the manufacturing process of fresh Cistanche deserticola raw materials from feeding to high yield to obtain powdery or small granular Cistanche deserticola extract rich in active substances such as echinacoside and verbascoside monomer compounds, effectively curbing and blocking And overcome the technical defect that the active ingredients such as echinacoside and verbascoside monomer compounds are severely degraded and lost due to the enzymatic reaction caused by the unfavorable drying treatment method of Cistanche, and greatly improve the economics of promoting sand-fixing plants parasitic Cistanche in the western desert value

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 1. Select the fresh fleshy stems of Cistanche tubulosa as raw material;

[0025] 2. Rinse the raw material in a washing tank with cold water, the temperature of the cold water is 4°C; pick it up, put it in a common industrial crushing device and a grinding device to crush and grind the fleshy stems of Cistanche deserticola, so that the cells are broken; crush and The grinding process is filled with liquid nitrogen, and the nitrogen concentration in the material is 0.5% (weight ratio); the measured material temperature is 15°C;

[0026] 3. Separating the milled Cistanche cell slurry with a common industrial centrifuge to obtain the Cistanche cell slurry;

[0027] 4. Use the usual industrial membrane separation process to use the Cistanche deserticola cell slurry to selectively screen and intercept macromolecular impurities such as polysaccharides and proteins, as well as impurities such as particles and sub-particles through ultrafiltration membrane pores, and further se...

Embodiment 2

[0031] 1. Select the fresh cistanche cistanche and the saline cistanche cistanche that are kept fresh in an industrial refrigerator with a storage temperature of 4°C as raw materials, and the ratio is 2:1;

[0032] 2. Put the raw materials in a washing tank and rinse them with industrially pure water. After picking them up, put them in a common industrial crushing device and grinding device to crush and grind the fleshy stems of Cistanche deserticola to break up the cells; the crushing and grinding process Charge CO 2 , CO in the material 2 The concentration is 0.8% (weight ratio), and 0.002% ascorbic acid, 0.002% gluconolactone and 0.003% citric acid (weight ratio) of the raw material weight are added; the temperature of the material is 16° C.;

[0033] 3. Separate the milled Cistanche cell slurry with an industrial centrifuge to obtain the Cistanche cell slurry; at the same time, add 200% pre-cooled industrial purified water (weight ratio) to the filter residue through two ...

Embodiment 3

[0039] 1. The quick-frozen succulent stems of Cistanche deserticola refrigerated at -52°C in an industrial freezer are used as raw materials;

[0040] 2. Put the raw materials in a washing tank and rinse them with industrially pure water. After picking them up, place them in a common industrial crushing device and grinding device to crush and grind the fleshy stems of Cistanche deserticola to break up the cells; the crushing and grinding process The sodium sulfite (weight ratio) of 0.002% of raw material weight is added in the process; The recorded material temperature is 3°C;

[0041] 3, the Cistanche cell slurry after milling is press-filtered with a common industrial filter press to obtain the Cistanche cell slurry; the filter residue is added to 60% pure water (weight ratio), and further ground into a slurry through a common industrial grinder, Then separated by an industrial centrifuge to obtain the broken cell washing liquid of Cistanche;

[0042] 4. After combining the...

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Abstract

The present invention provides a production method of cynamorlum extract full of active ingredients as echinacoside and veroascose glucoside monomeric compounds with high yield extracted from fresh cynamorlum succulent stem. The production method is implemented through systematic integrated technology of cytoclasis, serous extraction, membrane separation, high-temperature enzyme sterilization, spraying and drying, and other processes, so as to realize the manufacturing process from feeding the fresh cynamorlum to obtaining powdery or granular cynamorlum extract with high yield within 15 to 60 minutes. The present invention effectively inhibits, blocks and overcomes the technical defect of serious degradation and loss of active ingredients of echinacoside and veroascose glucoside monomeric compounds caused by enzyme catalysis reaction of poor drying method of cynamorlum. The major index ingredients of the obtained powdery or granular cynamorlum extract for measuring the cynamorlum quality are echinacoside and veroascose glucoside monomeric compounds, the productive rate of which is up to 15 to 23.4 percent (calculated in dry materials).

Description

technical field [0001] The invention relates to a production method for extracting cistanche deserticola extract rich in active components echinacoside and verbascoside monomer compounds from fresh fleshy stems. Background technique [0002] Herba Cistanches (Herba Cistanches) is a well-known traditional tonic Chinese medicine. The Cistanche deserticola recorded in the 2005 edition of "Chinese Pharmacopoeia" is the dry fleshy stem with scaly leaves of Cistanche deserticola Y.C.Ma and Cistanche tubulosa (Schrenk) R.Wight. "Shen Nong's Materia Medica" states: Cistanche "maintains the five labors and seven injuries. It is because the fire is weak and cannot produce soil, and it is not the root of the Qi. In the treatment of women's diseases, salty can soften the hardness and remove the blood. Cistanche stops the discharge of essence Drowning, remove the heat carbuncle in the stem, because it can guide the fire of asthenia, and the elderly are dry and stagnant, so it is benefic...

Claims

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Application Information

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IPC IPC(8): A61K36/64A61P15/08A61P15/10A61P1/10C07H1/08A61K135/00
Inventor 刘昕季青彭青云古德祥曹卉贾宝国
Owner SUN YAT SEN UNIV
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