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Method for preparing decocted ointment for treating headache

A decocting and decocting technology, which is applied in the field of medicine, can solve the problems of slow dissolving speed, slow dissolving speed of granules, and large dosage of medicine, so as to achieve the effect of convenient administration

Active Publication Date: 2008-06-11
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently reported Chinese patent medicine for treating headaches is Zhengtian Wan, which is a combination of Chinese and Western medicines. Its mechanism is to promote blood circulation and remove blood stasis, and it is equipped with Western medicine analgesics. Internal injury headache, blood deficiency and blood stasis liver yang headache, the effect is not good
[0003] At present, there are many traditional Chinese medicines for treating headaches, and the dosage forms are mostly granules and granules. Granules have disadvantages such as slow dissolution rate, large dosage, poor taste when taken orally, and inconvenient taking and carrying.
For example, the date of application is 1993.1.9, the application number is 93100050.5, the authorized announcement number is CN1047938C, and the title of the invention is a patent application for a traditional Chinese medicine for treating headache. This invention provides a Chinese medicine granule for treating headache. Certain and easier to take than a decoction, but slower dissolution still limits its use

Method used

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  • Method for preparing decocted ointment for treating headache

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take 4g of angelica, 4g of Chuanxiong, 2g of white peony root, 2g of rehmannia glutinosa, 10g of Uncle Teng, 10g of Miltonia Spatholobus, 10g of Prunella vulgaris, 10g of cassia seed, 10g of mother-of-pearl, 4g of Rhizoma Polygonum, and 0.5g of asarum;

[0022] The above eleven flavors, angelica, chuanxiong, white peony root, and corydalis are added with ethanol, heated to reflux, and the reflux liquid is stored in another container; the dregs and the other six flavors except Uncaria rehmanniae are decocted with water for three times. Add Uncaria uncariae, combine the decoction, concentrate under reduced pressure, add ethanol for alcohol precipitation, stand still, filter, combine the filtrate with the above-mentioned reflux liquid, recover ethanol under reduced pressure, concentrate the filtrate, and concentrate into a decoction to obtain the final product.

Embodiment 2

[0024] Take Angelica 7g, Chuanxiong 5g, Paeoniae Alba 6g, Rehmannia glutinosa 4g, Uncle Teng 14g, Millae Spatholobus 12g, Prunella vulgaris 14g, Cassia seed 12g, mother-of-pearl 14g, Yuanhu 5g, Asarum 1g for later use;

[0025] Add 70% ethanol to the above eleven flavors, angelica, Chuanxiong, white peony root, and Corydalis Corydalis, heat and reflux for 2 hours, and store the reflux liquid in another container; decoct the dregs and the other six flavors of rehmannia glutinosa except Uncaria chinensis three times, each time 1 hour, add Uncaria uncariae during the third decoction, combine the decoction, concentrate under reduced pressure to a relative density of 1.09-1.13 (55°C), add ethanol to make the alcohol content reach 65%, let stand for 24 hours, filter, The filtrate is combined with the above-mentioned reflux liquid, the ethanol is recovered under reduced pressure and concentrated to a decoction with a relative density of 1.10-1.20 (55°C).

Embodiment 3

[0027] Take 6.75g of Angelica, 6.75g of Chuanxiong, 5.4g of Radix Paeoniae Alba, 5.4g of Rehmannia Rehmanniae, 13.5g of Uncle Teng, 13.5g of Spatholobus Spatholobus, 13.5g of Prunella vulgaris, 13.5g of Cassia Seed, 13.5g of Mother of Pearl, 6.75g of Rhizoma Pediatricum, and Asarum 1.34g spare;

[0028] Add 70% ethanol to the above eleven flavors, angelica, Chuanxiong, white peony root, and Corydalis Corydalis, heat and reflux for 2 hours, and store the reflux liquid in another container; decoct the dregs and the other six flavors of rehmannia glutinosa except Uncaria chinensis three times, each time 1 hour, add Uncaria uncariae during the third decoction, combine the decoction, concentrate under reduced pressure to a relative density of 1.09-1.13 (55°C), add ethanol to make the alcohol content reach 65%, let stand for 24 hours, filter, The filtrate is combined with the above-mentioned reflux liquid, the ethanol is recovered under reduced pressure and concentrated to a thick p...

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Abstract

The invention provides a soft extract for curing headache and a process for preparation. Angelica sinensis, ligusticum wallichii, white peony root, radix rehmanniae, koxtox, milettia reticulata, prunella vulgaris, cassia seeds, pearl shell, rhizoma corydalis and asarum are prepared into extractum after being extracted in a certain method.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a decoction for treating headaches and a preparation method thereof. Background technique [0002] Headache is a common disease. Although some Chinese and Western medicines are available, the effect is not satisfactory, especially for the treatment of liver-yang headache of blood deficiency and blood stasis type. The curative effect of the medicine and the speed of onset of the medicine affect the patient key factor in quality of life. The commonly used Western medicine for the treatment of headaches has ergotamine caffeine, which is a vasodilator and is only suitable for cerebral arterial ischemic phlegm disease. The mechanism of action of the flunarizine decoction produced in 1988 is to selectively inhibit the entry of calcium into cells to reduce the constriction of veins. The currently reported Chinese patent medicine for treating headaches is Zhengtian Wan, which is a combination o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/06A61P25/04A61K35/56A61K35/618
Inventor 李永强郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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