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A method for coating the whole surface of a built-in prothesis

An inner surface and coating technology, applied in prostheses, coatings, colostomy devices, etc., can solve the problems of increased patient risk, decreased risk, poor adhesion of stent function, etc., and achieves the effect of lasting patency of vessels

Inactive Publication Date: 2008-04-30
HEMOTEQ AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the inherent problem of poor adhesion can also occur and degrade stent function, and thus lead to increased risk for the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0123] Example 1: Precoating of stents by means of the spraying method

[0124] The stand was attached to the rod of the rotator and sprayed with a 1% polyurethane solution by slowly moving the gun up and down at a very slow rotation speed. After spraying, the stent is a matte gray color, so it can be controlled by optical spraying. It is especially important that the edges are painted accurately, which can be ensured by additional surrounding spray. The scaffold is then allowed to dry.

example 2

[0125] Example 2: Polysulfone Spray Solution

[0126] 176 mg of polyether sulphone (polyether sulphone, PS, Odel(R) from Solvay) was weighed and made up to 20 g with chloroform (0.88% PS solution) and sprayed onto the stent as described in Example 1.

example 3

[0127] Example 3: Coating the entire surface of a sprayed stent by dip coating

[0128] Polyurethane was dissolved in THF, thus obtaining a 14% solution. The stent precoated according to Example 1 was carefully mounted on the appropriate mold.

[0129] Start by dipping the head of the tool with the stand mounted in pure THF until bubbles can be seen rising. Subsequently, the scaffold was slowly immersed in a 14% polyurethane solution. After 15 seconds, the core part was slowly taken out and quickly oriented horizontally, and the core part was turned over so that the polyurethane (PU) was evenly distributed on the support, and dried.

[0130] After the PU had stopped flowing, the core was dried under a fume hood and then tempered in a drying oven at 95°C for 45 minutes. After cooling, it was immersed in a warm 0.3% sodium dodecyl sulfate (SDS) solution to detach the bracket from the tool. After purification by running water and rinsing with 0.5 molar sodium hydroxide, it wa...

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PUM

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Abstract

Thin wall material used in the treatment of blocked blood vessels or trachea of patients is composed of a mesh of fine material which is made impervious by coating with a suitable material and to ensure complete coating a first thin coating is applied to the web material followed by a thick coating which covers the space between the webs.

Description

technical field [0001] The present invention relates to a method for coating the entire surface of a lattice-like or mesh-like endoprosthesis, wherein the endoprosthesis is initially provided with a thin layer covering the surface of the endoprosthesis material, i.e. struts forming a grid or grid; and subsequently coating the entire or respectively continuous surface area of ​​the endoprosthesis, wherein said coating of the entire or respectively continuous surface area will cover the struts as well as the individual struts gap between. Background technique [0002] Pathological changes regarding any body passage can lead to constriction or even total occlusion of the body passage. Arteriosclerosis and acute thrombosis are common causes of conditions such as myocardial infarction or correspondingly stroke. [0003] Another high risk associated with bodily passages is malignant and benign tumor growth. Due to the rapid and uncontrolled cell division, the tumor spreads to a...

Claims

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Application Information

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IPC IPC(8): A61L27/34A61L28/00A61L29/08A61L31/10
CPCC09D5/14A61L31/16A61L29/16A61L2300/606A61L29/085A61L27/54A61L31/10A61L27/34A61L2420/02A61F2/82A61F2/88
Inventor 罗兰·河瑞斯迈可·霍夫曼艾利克·霍夫曼马力塔·林森罗杰·卡司伯斯迈可拉·史凯尔尼克
Owner HEMOTEQ AG
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