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Pharmaceutical composition for cardiovascular and cerebrovascular diseases and method for preparing the same

A kind of technology of cardiovascular and cerebrovascular diseases and composition, applied in the field of medicine

Inactive Publication Date: 2008-04-02
吴浩山
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Currently using Salvia miltiorrhiza, Chuanxiong, Panax notoginseng, Astragalus and Storax, or Danshen, Chuanxiong, Sanqi, Astragalus, Storax, leech, Lingxiang and peach kernel, or Salvia, Chuanxiong, Sanqi, Astragalus, Storax, leech, Lingxiang , peach kernel, earthworm, Jiangxiang and Guangzao interaction, compatible prescriptions, for the preparation of pharmaceutical compositions for the treatment of cardiovascular and cerebrovascular diseases has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0229] Embodiment 1: the preparation of pharmaceutical composition tablet of the present invention

[0230] Prescription one:

[0231] Salvia miltiorrhiza 400g Chuanxiong 200g Notoginseng 300g Astragalus 150g Styrax 5g

[0232] Prescription two:

[0233] Salvia 300g Chuanxiong 300g Panax notoginseng 200g Astragalus 250g Styrax 15g

[0234] Prescription three:

[0235] Salvia miltiorrhiza 200g Chuanxiong 400g Notoginseng 100g Astragalus 350g Styrax 25g

[0236] Preparation Process:

[0237] Take Salvia miltiorrhiza and crush it into coarse powder, add 8 times the amount of water to decoct twice, each time for one hour, filter, combine the filtrate, concentrate to a concentrated solution with a relative density of 1.25-1.30 (50-60°C), and refrigerate for later use; Crush Rhizoma Chuanxiong into coarse powder (d=0.3~0.5cm), soak in water for 4 hours, extract the volatile oil by steam distillation for 5 hours, collect the volatile oil, mix the volatile oil with Styrax styra...

Embodiment 2

[0238] Embodiment 2: the preparation of pharmaceutical composition granule of the present invention

[0239] Prescription one:

[0240] Salvia 400g Chuanxiong 400g Panax notoginseng 100g Astragalus 150g Leech 140g Styrax 5g Lingxiang 100g

[0241] 140g peach kernels

[0242] Prescription two:

[0243] Salvia 300g Chuanxiong 300g Panax notoginseng 200g Astragalus 250g Leech 100g Styrax 15g Lingxiang 200g

[0244] 100g peach kernel

[0245] Prescription three:

[0246] Salvia 200g Chuanxiong 200g Panax notoginseng 300g Astragalus 350g Leech 60g Styrax 25g Lingxiang 300g

[0247] 60g peach kernels

[0248] Preparation Process:

[0249] Take salvia miltiorrhiza, leeches, and two herbs and crush them into coarse powder, add 8 times the amount of water to decoct twice, each time for one hour, filter, combine the filtrates, and concentrate to a concentrated concentration with a relative density of 1.25-1.30 (50-60°C). Separately take Chuanxiong and Linglingxiang and grind t...

Embodiment 3

[0250] Embodiment 3: the preparation of pharmaceutical composition capsule of the present invention

[0251] Prescription one:

[0252] Salvia 300g Chuanxiong 300g Panax notoginseng 200g Astragalus 250g Leech 100g Earthworm 100g Styrax 15g

[0253] Linglingxiang 200g, Jiangxiang 100g, peach kernel 100g, jujube 80g

[0254] Preparation Process:

[0255] Take the three herbs of salvia miltiorrhiza, leech, and earthworm, and grind them into coarse powder, add 8 times the amount of water to decoct twice, each time for one hour, filter, combine the filtrates, and concentrate to a relative density of 1.25-1.30 (50-60°C). Concentrated solution, refrigerated for later use; additionally take Chuanxiong, Jiangxiang and Linglingxiang three herbs and grind them into coarse powder (d=0.3~0.5cm), soak in water for 4 hours, extract volatile oil by steam distillation for 5 hours, collect volatile oil, volatile oil and Mix storax and clathrate with β-cyclodextrin; take another four medici...

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PUM

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Abstract

The invention belongs to the medical technical field and discloses a drug combination for the cardiovascular disease and the preparation method of the drug combination. The drug combination contains the pharmacodynamic components of the raw materials of drugs of danshen root, Szechwan lovage rhizome, panax notoginseng, milkvetch root and storax. In order to achieve a better curative effect, a leech, tonka beans and peach nuts can also be added into the drug combination; in order to further improve the curative effect, rosewood, axillary choerospondias fruit and earthworms can be added into the drug combination. The drug combination of the invention has the efficacies of promoting the circulation of qi to induce resuscitation, activating blood circulation for removing blood stasis, dredging channels for alleviating pain etc. and is used for preparing the drugs for remedying the cerebral infarction convalescence of the coronary heart disease, the angina pectoris or the arteriosclerosis, the syndrome of which belong to the qi stagnation and blood stasis with the symptoms of chest pain, oppression in the chest, shortness of breath, heart throb, inefficaciousness of limbs, inarticulacy etc. The drug combination of the invention can be made into any preparation type, which is acceptable in the clinic and the pharmacy, and the oral preparation is preferential.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for cardiovascular and cerebrovascular diseases and a preparation method thereof. 2. Background technology [0002] Cardiovascular and cerebrovascular disease is the second largest disease that seriously endangers human health and causes human death, and its morbidity and mortality are increasing year by year. [0003] Cardiovascular diseases include heart disease, high blood pressure, hyperlipidemia, etc. It has the characteristics of "high morbidity, high mortality, high disability rate, high recurrence rate" and "many complications", and its etiology is mainly arteriosclerosis. Arteriosclerosis refers to the deposition of fat and cholesterol on the inner wall of arteries, accompanied by the formation of fibrous tissue and calcification. When this lesion develops into the coronary arteries of the heart, it will form coronary heart d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K36/73A61P9/10A61K35/62A61K35/64
Inventor 黄振华
Owner 吴浩山
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