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Traditional Chinese medicine compound formulated product for treating hyperkinetic symptom and method of producing the same and use of the same

A compound preparation, a technology for ADHD, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., and can solve the problem of high morbidity

Inactive Publication Date: 2008-02-27
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the high incidence of multiple diseases in children, it is still of practical significance to develop new traditional Chinese medicines with less toxic and rich effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1) Take 200g of Acorus calamus coarse powder, add 2 times the volume-to-weight ratio of water, steam distill for 0.5h to extract volatile oil, and obtain volatile oil A, water extract B and Acorus calamus medicinal residue;

[0020] 2) Take 270g of astragalus, 200g of polygala, 200g of shichangpu, 200g of poria cocos, and 150g of licorice, mix them with the dregs of shichangpu after extracting the volatile oil, and add 2 times the volume to weight ratio of water to reflux and extract once. The extraction time is 0.5h, and the water is obtained. Extract C;

[0021] 3) The above-mentioned water extracts B and C were combined, and after centrifugation, the obtained supernatant was concentrated to a relative density of 1.1, and dried under reduced pressure to obtain a dry extract;

[0022] 4) pulverize the above-mentioned dry extract, and sieve to obtain dry extract powder;

[0023] 5) Add volatile oil A to β-cyclodextrin whose volume-to-weight ratio is 1 times for inclusi...

Embodiment 2

[0026] 1) Take 300 g of Shichangpu decoction pieces, add water with a volume-to-weight ratio of 20 times, steam distillation for 20 hours to extract volatile oil, and obtain volatile oil A, water extract B and Shichangpu medicinal residue;

[0027] 2) Take 405g of Radix Astragali, 300g of Polygala, 300g of Poria cocos, 300g of Poria cocos, 225g of licorice, mix with the herbal residues of Acorus japonica after extraction of volatile oil, and add 20 times the volume to weight ratio of water to reflux and extract for 3 times. The extraction time is 4 hours, and the water is obtained. Extract C;

[0028] 3) The above-mentioned water extracts B and C were combined, and after centrifugation, the obtained supernatant was concentrated to a relative density of 1.25, spray-dried to obtain a dry extract;

[0029] 4) pulverize the above-mentioned dry extract, and sieve to obtain dry extract powder;

[0030] 5) Add the volatile oil A to the β-cyclodextrin whose volume-to-weight ratio is ...

Embodiment 3

[0033] 1) Take 100g of Shichangpu decoction pieces, add water with a volume-to-weight ratio of 10 times, steam distill for 4 hours to extract volatile oil, and obtain volatile oil A, water extract B and Shichangpu medicinal residue;

[0034] 2) Take 135g of Radix Astragali, 100g of Polygala, 100g of Poria cocos, 100g of Poria cocos, 75g of licorice, mix with the volatile oil extracted from Acorus radix, add 10 times the volume to weight ratio of water, and reflux extract twice. The extraction time is 2h, and the water is obtained. Extract C;

[0035] 3) The above-mentioned water extracts B and C were combined, and after centrifugation, the obtained supernatant was concentrated to a relative density of 1.15, dried under reduced pressure to obtain a dry extract;

[0036] 4) pulverize the above-mentioned dry extract, and sieve to obtain dry extract powder;

[0037] 5) Add volatile oil A to β-cyclodextrin with a volume-to-weight ratio of 10 times for clathrate to obtain β-cyclode...

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Abstract

The invention discloses the process for preparing Chinese compound preparation for treating hyperkinetic symptom and use, wherein the preparation comprises astragalus root 1-20 weight parts, polygala root 1-20 weight parts, grassleaved sweetflag rhizome 1-20 weight parts, pseudostellaria root 1-20 weight parts, poria cocos wolf 1-20 weight parts and licorice root 1-20 weight parts. The preparing process consists of water extraction, centrifugal treatment, mixing concrete powder, inclusion compound and auxiliary materials to obtain the granule form preparation.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating ADHD, a preparation method and application thereof. Background technique [0002] ADHD (attention deficit hyperactivity disorder, ADHD) is the abbreviation of children's hyperactivity syndrome, that is, mild brain dysfunction syndrome, which is called attention deficit hyperactivity disorder in clinical medicine, and is a relatively common children's behavior disorder syndrome. . The children have normal or near-normal intelligence, hyperactivity, inattention, emotional instability, impulsive willfulness, and learning difficulties in varying degrees. The domestic incidence rate of ADHD in children is 5%-9%, accounting for the first place in children's psychological clinics. The etiology and pathogenesis of this disease are still unclear, and there are various treatment methods. [0003] Doctor trained in Western medicine often has for the treatment drug of this...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61P25/00
Inventor 张琳田景奎刘洪辉刘洪梅廖莉谷希达孙铭遥
Owner ZHEJIANG UNIV
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