Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Eye drops used for treating cataract and cloudy vitreous turbidity of persons in middle and old age, and method for preparing the same

A cataract and vitreous technology, applied in the field of chemical medicine eye drops production technology, can solve problems such as vitreous turbidity

Inactive Publication Date: 2008-02-27
程雪翔
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tiopronin currently has various dosage forms such as tablets, capsules and other oral solids and injections at home and abroad, but there is no eye drop dosage form at home and abroad for the treatment of middle-aged and elderly cataracts and vitreous opacity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] prescription:

[0032] Tiopronin 0.2g

[0033] Sodium Hyaluronate 30mg

[0034] Appropriate amount of related accessories

[0035] Water for injection 10ml

[0036] Preparation method: Take tiopronin and related auxiliary materials and dissolve them in appropriate amount of water for injection.

[0037] Take the prescribed sodium hyaluronate in water for injection, stir continuously at 60-70°C to make it fully swell, boil, and filter while hot with a microporous membrane.

[0038] Slowly add the filtered sodium hyaluronate solution into the tiopronin solution, stir evenly while adding, adjust the pH value to 6.0-8.0 with borax, and the osmotic pressure is 260-420mOsm·kg -1 h 2 O, add water for injection to a sufficient amount, filter to obtain a clear solution, sub-package, and check the quality to get final product.

Embodiment 2

[0040] prescription:

[0041] Tiopronin 0.2g

[0042] Sodium Hyaluronate 40mg

[0043] Sodium chloride 20mg

[0044] Appropriate amount of related accessories

[0045] Water for injection 10ml

[0046] Preparation method: Dissolve tiopronin, sodium chloride and related auxiliary materials in appropriate amount of water for injection respectively.

[0047] Take the prescribed sodium hyaluronate in water for injection, stir continuously at 60-70°C to make it fully swell, boil, and filter while hot with a microporous membrane.

[0048] Slowly add the filtered sodium hyaluronate solution into the tiopronin solution, stir evenly while adding, adjust the pH value to 6.0-8.0 with borax, and the osmotic pressure is 260-420mOsm·kg -1 h 2 O, add water for injection to a sufficient amount, filter to obtain a clear solution, sub-package, and check the quality to get final product.

Embodiment 3

[0050] prescription:

[0051] Tiopronin 0.2g

[0052] Sodium Hyaluronate 30mg

[0053] Sodium chloride 30mg

[0054] Appropriate amount of related accessories

[0055] Water for injection 10ml

[0056] Preparation method: Dissolve tiopronin, sodium chloride and related auxiliary materials in appropriate amount of water for injection respectively.

[0057] Take the prescribed sodium hyaluronate in water for injection, stir continuously at 60-70°C to make it fully swell, boil, and filter while hot with a microporous membrane.

[0058] Slowly add the filtered sodium hyaluronate solution into the tiopronin solution, stir evenly while adding, adjust the pH value to 6.0-8.0 with borax, and the osmotic pressure is 260-420mOsm·kg -1 h 2 O, add water for injection to a sufficient amount, filter to obtain a clear solution, sub-package, and check the quality to get final product.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an eye drops and preparing method to treat cataract for person in middle and old age and vitreous opacity, which is made of sulfur puluonin and corresponding auxiliary materials. The invention has relatively stable quality and effect to be carried and intaked safely and heathly, which improves the quality standard and enlarges the drug kinds to satisfy the need of the people for drugs.

Description

technical field [0001] The invention relates to the technical field of preparation of chemical medicine eye drops, in particular to an eye drop for treating middle-aged and elderly cataracts and vitreous turbidity and a preparation method thereof. Background technique [0002] As we all know, cataract and vitreous opacity are important causes of blindness in my country, and are also the eye diseases with the highest blinding rate in the world. With the prolongation of human life expectancy, the incidence of eye diseases such as cataract in the middle-aged and elderly people will be higher, which will undoubtedly cause a greater burden on the elderly, families and society. There are several corresponding medicines that come out at present, in clinical use, their efficacy is controversial, such as potassium iodide, which came out the earliest, has no obvious effect in clinical use, although glutathione can delay the formation of cataracts, but it Can not prevent the progressi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/197A61K47/36A61P27/12
Inventor 程雪翔
Owner 程雪翔
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com