Portable bilayer lipid membrane electrochemical gene sensor

Abstract

This invention discloses one portable double resin film electro-chemical sensor, which comprises level constant module, central control module and test electrode, wherein, the constant level module is composed of high input resistance computation amplifier as center error amplification device; reference electrode and given electrode are comparing to be sent to band filter and work frequency limit wave device for process to remove noise and interference through power amplifier to output test electrode; central control module also comprises data collection unit, progress switch unit, input display unit and single machine.

Description

technical field [0001] The invention relates to a bioelectrochemical sensor, in particular to a portable electrochemical gene sensor. Background technique [0002] At present, DNA detection usually adopts PCR detection method, which has high sensitivity, but also has its own shortcomings. Because PCR detection method enlarges a very small amount of DNA by a million times, false positives are more common while high sensitivity . [0003] Since the 1990s, various biological detection systems based on biosensor technology have emerged rapidly, and some fast and modern technology detection methods have emerged continuously. This technology has also been gradually applied to the detection field. The electrochemical detection method has the advantages of simple sample preparation, The test time is short, the cost is low, and the sensitivity is high, and the DNA does not need to be labeled. Electrochemical gene sensors are the product of the combination of biotechnology and elect...

AI Technical Summary

Problems solved by technology

[0005] In order to solve the technical problem in the prior art that often needs to be marked in the process of detecting DNA, the present invention provides a small-volume portable double-layer lipid membrane electrochemical gene sensor. By modifying the electrode surface, the DNA fragments or probes are immobilized on the surface of the electrode, and no labeling is required during the detection process. The portable electrochemical gene sensor of the present invention is conveniently applied to the detection of DNA. By measuring the changes in electrochemical parameters before and after fixation and before and after hybridization, it is determined The content of the substance to be tested

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