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Traditional Chinese medicine composition capable of resisting infection

A composition and anti-infection technology, which is applied in the field of anti-infection traditional Chinese medicine composition to treat respiratory tract and gastrointestinal tract infections, and can solve problems such as unclear impurities, difficult control of product quality, and easy adverse reactions

Inactive Publication Date: 2011-07-06
HUNAN JIUDIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many anti-infective traditional Chinese medicines on the market, such as Compound Daqingye Granules, Lianzhi Anti-inflammatory Tablets, and Shuanghuanglian Injection, etc., due to their defects such as many medicinal flavors, complex ingredients, and unclear impurities, it is difficult to Product quality is difficult to control, and it is easy to cause adverse reactions, so the inventor has researched and developed the present invention accordingly.

Method used

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  • Traditional Chinese medicine composition capable of resisting infection
  • Traditional Chinese medicine composition capable of resisting infection
  • Traditional Chinese medicine composition capable of resisting infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Weigh 3000g of Scutellaria baicalensis, 120g of dry extract of Ficus microphylla (equivalent to 1000g of Ficus microphylla) and 2500g of Huangteng, and prepare oral liquid as follows:

[0067] A. Weigh Scutellaria baicalensis in proportion, add 12 times the amount of water, soak for 5 hours, and decoct 3 times, each time for 1 hour. Concentrate the filtrate to 5 times the amount of feed, adjust the pH to 1-2, keep it warm at 80°C for 1 hour, let it stand for 24 hours, wash the precipitate with water to pH 5.0, continue to wash with 70% ethanol to pH 7.0, and dry at low temperature. That is to get baicalin;

[0068] B. Weigh Huangteng in proportion, crush it with 0.2% H 2 SO 4 The solution was soaked 4 times, the soaking time was 48 hours, 24 hours × 3, the extract was adjusted to pH 8 with NaOH, allowed to stand for precipitation to remove impurities, the filtrate was salted out with 9% NaCl (iodized salt), left for a day and night, filtered, The precipitate is dried...

Embodiment 2

[0071] Weigh 250g of baicalin (equivalent to 5500g of Scutellaria baicalensis), 90g of dry extract of Ficus microphylla (equivalent to 1000g of Ficus microphylla ) and 75g of palmatine (equivalent to 1500g of Huangteng vine), and prepare capsules as follows:

[0072] Grind the dry extract of Ficus microphylla into powder, mix it with baicalin and palmatine evenly, add appropriate amount of pregelatinized starch, sucrose, and magnesium stearate as corresponding auxiliary materials, granulate with 70% ethanol, granulate, mix Evenly, press into tablets. Prepare 1000 tablets.

Embodiment 3

[0074] Weigh 180g of baicalin (equivalent to 5040g of Scutellaria baicalensis), 200g of dry extract of Ficus microphylla (equivalent to 1500g of Ficus microphylla) and 45g of palmitine (equivalent to 800g of Huangteng vine), and make capsules according to the following steps.

[0075] Grind and pulverize the baicalin, dry extract of Ficus microphyllum and patoin in proportion, and then mix them evenly. Granulate, granulate, mix evenly, pour into gelatin capsule shell, prepare 1000 capsules.

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Abstract

The invention provides an anti-infective Chinese medicinal composition which is prepared from active constituents including baikal skullcap root or its active constituents, active constituent of ficusmicro carpal or its extract, active constituent of fibraurea stem or its extract, active constituent of fibraurea stem extract and right amount of pharmaceutically acceptable auxiliary materials.

Description

field of invention [0001] The invention belongs to the field of traditional Chinese medicine, and relates to an anti-infection traditional Chinese medicine composition, especially for treating respiratory tract and gastrointestinal infection diseases. Background technique [0002] Infectious diseases are common diseases. With the growth and aging of my country's population, the treatment of infectious diseases accounts for an increasing proportion of clinical treatment. Its incidence rate is increasing year by year, and the range of the onset population is wider and wider. Because anti-infective drugs have a wide range of applications, they have been used in large quantities in clinical practice for a long time, resulting in serious irrational and abuse of anti-infective drugs. The incidence of adverse reactions to clinical anti-infective drugs has increased year by year, and bacterial drug resistance has become increasingly serious. , Some anti-infective drugs have reduced...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/539A61K31/4745A61K36/59A61P31/00A61K31/7048A61K36/60
Inventor 朱志宏卜振军杨静
Owner HUNAN JIUDIAN PHARMA
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