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A compound suspension of molluscicidal drug niclosamide ethanolamine salt and its preparation method

A technology of niclosamide ethanolamine salt and suspending agent, which is applied in the field of molluscicide drug niclosamide ethanolamine salt compound suspending agent and its preparation field, can solve the problems of high cost and drug resistance, increase the effect of killing snails, eliminate Bubbles, the effect of improving dispersibility

Active Publication Date: 2007-08-01
JIANGSU ESSENCE AGROCHEM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to overcome the high cost of existing products and the possible drug resistance problems, and provide a low-cost niclosamide ethanolamine salt compound suspending agent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] In terms of mass percentage, 1 part of niclosamide ethanolamine salt, 5 parts of metaldehyde, 10 parts of sodium lignosulfonate, 10 parts of alkylphenol polyoxyethylene ether, 10 parts of xanthan gum, 64 parts of water, mixed Finally, add it to a ball mill jar for grinding, and grind on a planetary ball mill at 500 r / min for 1 hour to make the particle size less than 5 μm to obtain a compound suspension concentrate of niclosamide ethanolamine salt.

Embodiment 2

[0023] In terms of mass percentage, 10 parts of niclosamide ethanolamine salt, 1 part of metaldehyde, 10 parts of sodium lignosulfonate, 10 parts of sodium dodecylbenzenesulfonate, 10 parts of xanthan gum, 59 parts of water, After mixing, put it into a ball mill jar for grinding, and grind on a planetary ball mill at 200 r / min for 2 hours, so that 95% of the particle size is less than 5 μm, to obtain a compound suspension concentrate of niclosamide ethanolamine salt.

Embodiment 3

[0025] In terms of mass percentage, 25 parts of niclosamide ethanolamine salt, 1 part of metaldehyde, 5 parts of alkylnaphthalene sulfonate formaldehyde condensate, 5 parts of alkylphenol polyoxyethylene ether, 0.05 part of xanthan gum, 63.95 Parts of water, mixed, added to a ball mill for grinding, and ground on a planetary ball mill at 380 r / min for 4 hours, so that 95% of the particle size is less than 5 μm, to obtain the niclosamide ethanolamine salt compound suspension.

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PUM

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Abstract

The invention discloses a snail control insecticide of compound niclosamide ethanolamine salt suspending agent which comprises the constituents (by weight portion) of niclosamide ethanolamine salt 1-50 parts, methaldehyde 0.01-5 parts, dispersing agent 1-20 parts, wetting agent 0.5-20 parts, and thickening agent 0.05-10 parts, and balancing water. The invention also discloses the process for preparing the suspending agent.

Description

technical field [0001] The invention belongs to the technical field of pesticides, and in particular relates to a snail-killing drug niclosamide ethanolamine salt compound suspension and a preparation method thereof. Background technique [0002] Niclosamide is the only molluscicide recommended by WHO since 1972. Niclosamide was prepared in China in the 1960s. This drug is poorly soluble in water, but soluble in organic solvents or alkaline solutions. Niclosamide is usually made into 50% niclosamide ethanolamine salt wettable powder for killing snails. In addition, niclosamide can be made into 70% conchicide wettable powder, 25% emulsifiable concentrate, or 25% suspension concentrate. Due to the unsatisfactory dissolubility and dispersibility of various powders of niclosamide, small lumps of precipitates are easy to block spraying equipment, resulting in difficulty in use and uneven concentration of liquid medicine, resulting in decreased molluscicide effect and higher cos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N37/48A01N25/04A01P9/00A01N35/02
Inventor 戴建荣张申伟马敏
Owner JIANGSU ESSENCE AGROCHEM
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