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Vagina external-use medicine composition and its preparing method and use

A technology for external use of drugs and compositions, which is applied in directions such as drug combination, drug delivery, and pharmaceutical formulations, can solve the problems of inconvenient use and portability, insignificant curative effect, and long use cycle, and achieves convenient portability, short medication time, and exact curative effect. Effect

Inactive Publication Date: 2009-08-12
四川明星药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned commonly used external medicines have defects such as long service life, inconspicuous curative effect, inconvenient use and carrying, and unpleasant smell.

Method used

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  • Vagina external-use medicine composition and its preparing method and use
  • Vagina external-use medicine composition and its preparing method and use
  • Vagina external-use medicine composition and its preparing method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 The preparation method of medicinal lotion of the present invention

[0028] 400g of pine, 350g of sophora, 100g of cork, 50g of kudiding, 40g of cnidium, 30g of licorice, 0.5g of borneol;

[0029] The production method of medicine of the present invention is:

[0030] For the above seven flavors, take pine medicinal materials, steam distill for 2-3 hours, collect volatile oil and aromatic water and store them in another device. Use 10-18 times of 0.6% v / v hydrochloric acid solution as a solvent for Sophora sophora and Cortex Phellodendri, soak for 24 hours and then percolate, and the percolation liquid is concentrated into a clear paste for later use; (Sophora sophora mainly contains alkaloid components, such as Kumarin etc., according to the nature of alkaloids, exist in the form of salt with acid solution, easily soluble in sour water, so hydrochloric acid is selected as the extraction solvent. Containing berberine and phellodendron are alkaloid compone...

Embodiment 2

[0033] Embodiment 2 The preparation of suppository of the present invention

[0034] 800g of pine, 700g of sophora, 150g of cork, 100g of kudiding, 100g of cnidium, 80g of licorice, 1g of borneol;

[0035]For the above seven flavors, take pine medicinal materials, steam distill for 2-3 hours, collect volatile oil and aromatic water and store them in another device. Use 10-18 times of 0.6% v / v hydrochloric acid solution as a solvent for Sophora sophora and Cortex Phellodendri, soak for 24 hours and then percolate, and the percolation liquid is concentrated into a clear paste for later use; (Sophora sophora mainly contains alkaloid components, such as Kumarin etc., according to the nature of alkaloids, exist in the form of salt with acid solution, easily soluble in sour water, so hydrochloric acid is selected as the extraction solvent. Containing berberine and phellodendron are alkaloid components in Cortex Phellodendri, so it is selected Hydrochloric acid solution extraction);...

Embodiment 3

[0037] Embodiment 3 Preparation of capsules of the present invention

[0038] 800g of pine, 500g of sophora, 200g of cork, 70g of kudiding, 70g of cnidium, 50g of licorice, 1.5g of borneol;

[0039] For the above seven flavors, take pine medicinal materials, steam distill for 2-3 hours, collect volatile oil and aromatic water and store them in another device. Use 10-18 times of 0.6% v / v hydrochloric acid solution as a solvent for Sophora sophora and Cortex Phellodendri, soak for 24 hours and then percolate, and the percolation liquid is concentrated into a clear paste for later use; (Sophora sophora mainly contains alkaloid components, such as Kumarin etc., according to the nature of alkaloids, exist in the form of salt with acid solution, easily soluble in sour water, so hydrochloric acid is selected as the extraction solvent. Containing berberine and phellodendron are alkaloid components in Cortex Phellodendri, so it is selected Hydrochloric acid solution extraction); Kudid...

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Abstract

The invention provides a pharmaceutical composition for vaginal external use, which is a preparation prepared from the following raw materials: Sophora sophora, Pinus pine, Phellodendron cork, Ding kudiding, Fructus Cnidii, Borneol and licorice. The invention also provides a preparation method of the pharmaceutical composition and its application in the preparation of antibacterial, anti-inflammatory, anti-trichomonas and antipruritic drugs for topical vaginal administration; experiments show that the drug of the present invention has definite curative effect, clear therapeutic range, and carries The invention is convenient, has a delicate medicinal taste, and provides quality control standards, so that the medicine of the invention is safe, effective, stable and controllable.

Description

technical field [0001] The invention relates to a pharmaceutical composition made from traditional Chinese medicines, in particular to an external pharmaceutical composition for treating gynecological vaginitis, which belongs to the field of traditional Chinese medicines. Background technique [0002] According to "China Maternal and Child Health Care" and other literature reports, the survey results show that the incidence of various gynecological inflammations and diseases such as female genital itching, leucorrhea, and lower body odor is as high as 69% among adult women; WHO World Health Organization According to statistics, the incidence rate of gynecological diseases is 40%, and that of married women is almost 70%. If the above-mentioned gynecological inflammation is not treated in time, it will seriously affect the quality of life and family happiness, as well as study and work, and cause family economic burden; even cause constipation, obesity, infertility and other d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K36/66A61K36/61A61K36/489A61K36/484A61K36/234A61K31/045A61K9/00A61P15/02
Inventor 姜惠民
Owner 四川明星药业有限责任公司
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