Selenium-rich hedgehog fungus extract preparation for treating colitis, gastritis and stomach cancer and its preparing process
A technology of Hericium erinaceus extract and colitis, which is applied in the field of Hericium erinaceus extract preparations, can solve the problems such as there are no relevant reports on the industrial production of selenium-enriched Hericium erinaceus extract preparations, and achieves significant selenium enrichment effect and improved Nutritional status, easy operation effect
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[0027] The Hericium erinaceus used in the present invention has a strain number of 5.580, which was introduced from the China Common Microorganism Culture Collection and Management Center. Three-stage submerged fermentation culture is adopted, the fermentation process adopts aseptic operation, the extraction process adopts plate and frame separation, double-effect concentration, spray drying, and excipients are added according to the conventional process to make selenium-enriched Hericium erinaceus extract particles.
[0028] The preparation method of selenium-enriched Hericium erinaceus extract is:
[0029] A. Incline cultivation
[0030] Medium: PDA comprehensive medium + 33.3mg / 100ml sodium selenite (Na 2 SeO 3 ·5H 2 O), make the selenium content in the culture medium reach 100 μ g / ml.
[0031] Culture conditions: Culture at 25°C±1°C for 8-10 days at a constant temperature.
[0032] B. Liquid shake flask culture:
[0033] Medium: bran 5%, glucose 1%, peptone 0.1%, KH ...
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