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Hemostatic material in medical use

A technology of bone wax and lactic acid, applied in the types of packaging items, special packaging items, applications, etc., can solve the problem of non-degradation of bone wax, and achieve the effects of good biocompatibility, good ductility, and obvious hemostatic effect.

Inactive Publication Date: 2007-10-24
HUIZHOU HUAYANG MEDICAL EQUIP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] What the present invention aims to solve is the problem that bone wax cannot be degraded in the human body in the prior art, and provides a medical absorbable bone wax that can be completely degraded in the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0025] 1. Weigh 100 grams of DL-lactic acid, add it to a 250ml three-necked bottle, and heat it up to 120°C under vacuum, with a vacuum of 5-10mmHg, and stir for 2-3 hours. Then the temperature was raised to 140-150° C., the vacuum degree was 5-10 mmHg, and the reaction was stirred for 10 hours.

[0026] Stop vacuuming, and pour high-purity nitrogen into the three-necked bottle to maintain equilibrium with atmospheric pressure. Add 10 grams of polyether diol (molecular weight 10000), 10 grams of poly-DL-lactic acid (intrinsic viscosity 2.35), and stir for 30 minutes.

[0027] The product obtained after cooling is the finished medical absorbable bone wax.

[0028] Pack the medical absorbable bone wax well, sterilize it with cobalt 60 radiation, or sterilize it with ethylene oxide, and then it can be used.

[0029]2. Weigh 95 grams of glycolic acid (ie, glycolic acid), add it to a 250ml three-necked bottle, and heat up to 120°C under vacuum, with a vacuum of 5-10mmHg, and stir...

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PUM

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Abstract

A medical styptic material able to be fully absorbed and degradated is composed of the basic material prepared by fusion polycondensation reaction of low-molecular poly-DL-lactic acid or poly-L-lactic acid or polyethanol-acid copolymer / mixture, and the auxiliary which may be polyether diol, polyether triol, high-molecular polylactic acid, high-molecular glycolide-lactide copolymer, high-molecular caprolactone-lactide copolymer, or high-molecular caprolactone-glycolide copolymer through fusion and mixing.

Description

technical field [0001] The invention relates to a medical absorbable bone wax, in particular to a completely biodegradable bone wax that can be absorbed by the human body. Background technique [0002] At present, bone cancellous hemostatic materials in orthopedics, thoracic surgery and neurosurgery are mainly non-degradable bone wax products, which mainly rely on their unique hardness, toughness and viscosity and their mechanical barrier function to achieve hemostasis. At present, many hospitals in China are self-produced and used for their own use. There is no uniform formula and standard. Beeswax and vaseline, beeswax, refined sesame oil and salicylic acid, beeswax, peanut oil and aspirin are mostly used. Most of them can not achieve the ideal hardness, toughness and viscosity, and the hemostatic effect is poor. The main product in the domestic market is the medical bone wax produced by the U.S. Johnson & Johnson, and the medical sterile bone wax (patent application numb...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/14A61L31/04A61L24/00A61L33/00A61L27/00
Inventor 潘高峰冯宝星
Owner HUIZHOU HUAYANG MEDICAL EQUIP
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