Immune priming to accelerate/enhance immune response through administration of natural immune modulator

Abstract

A method and compound for altering the status of both innate and adaptive immune pathways in both animals and humans are disclosed. The status alteration results in the immune response being primed whereby an accelerated and more robust response is generated when the animal or human is challenged by pathogens that lead to a wide range of disease states. The disclosed method utilizes a compound derived from a lipopolysaccharide (LPS) of gram-negative bacteria. The compound itself is a natural product with no observed adverse environmental impact. By priming the immune pathways according to the disclosed inventive concept, the severity of various disease states can be reduced, can be resolved more quickly, or can be avoided entirely.

Description

CROSS REFERENCE TO RELATED APPLICATION[0001]This application is a US. Non-provisional patent application of U.S. Provisional Patent Application No. 63 / 044,841, entitled “Immune Priming to Accelerate / Enhance Immune Response Through Administration of Natural Immune Modulator,” filed Jun. 26, 2020, which is herein incorporated by reference in its entirety for all purposes.TECHNICAL FIELD[0002]The present disclosed inventive concept relates to immune systems in animals and humans. More particularly, the disclosed inventive concept relates to a method and treatment using a compound that alters the status of both innate and adaptive immune pathways in both animals and humans. The status alteration results in the immune response being primed whereby an accelerated and more robust response is generated when the animal or human is challenged by pathogens that lead to a wide range of disease states.BACKGROUND OF THE INVENTION[0003]Substantial economic losses in many animal industries, includi...

AI Technical Summary

Benefits of technology

The invention is a new compound that can be added to animal feed, like poultry feed, to improve its effectiveness in preventing and treating various diseases. The compound is easy to administer, cost-effective, and works by stimulating the immune system, making it better able to fight off infections. The result is a stronger, more robust response when challenged by disease, which can lead to improved growth efficiency and reduced need for antibiotics. The compound can also be used in humans as a dietary supplement to improve immune health.

Problems solved by technology

Substantial economic losses in many animal industries, including the poultry industry, are most often the result of disease.

Diseases in flocks often result in reduced productivity or compromises in the safety or quality of the final product introduced into the food supply.

Prevention and treatment of poultry disease adds significantly to poultry production costs.

While this approach has shown some benefit, vaccines are known to suffer from very poor effectiveness in controlling the disease over time.

Experimentation has shown that a vaccine used in conjunction with a supplement such as a probiotic may improve outcome, but this approach adds to production cost.

Secondly, coccidiosis treatment today is accomplished conventionally through the use of antibiotics and ionophores, both of which are costly.

Other synthetic treatment compounds and chemical agents are known and in use, but are not as effective as conventional antibiotics or ionophores.

Thirdly, drug resistance to antibiotics, ionophores, and pathogen-specific treatment compounds is increasing largely due to overuse, thereby significantly compromising the effectiveness of these treatments.

Concurrently, there has been no approval of new drugs in any of these categories for many years.

Fourthly, even if current treatments were economical and effective as claimed, these approaches would still be regarded as unsatisfactory because the medication must be included in the animal's feed for the full duration of the grow period to be fully effective.

This requirement adds significant cost to feed for the entire grow period.

Images