Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method and ocular implant for transmission of nerve-stimulation light

a technology of nerve stimulation and ocular implants, which is applied in the field of methods and apparatus for vision restoration and optical nerve stimulation, can solve the problems of slowing the disease progression, inherently hindering, and little hope for maintaining vision, and achieves enhanced perceived image resolution and enhanced patient comfor

Inactive Publication Date: 2014-08-21
LOCKHEED MARTIN CORP
View PDF9 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention uses infrared light to stimulate vision nerves and recreate sight in patients with lost vision. This technology provides higher precision and selectivity of stimulation without the need for tissue contact. The invention utilizes infrared light to cause action potentials in the retinal nerves with the purpose of recreating sight. The ocular implant is designed to require no internal or external electrical-power source and does not impede movement of the eyeball after surgical implantation. The invention provides improved resolution down to a group of nerves, or even the individual nerve level, with sufficient energy density so as to cause desired action potentials in the targeted nerves. The present invention offers enhanced patient comfort and enhanced perceived image resolution.

Problems solved by technology

For many patients suffering from retinal degenerative diseases such as advanced or age-related macular degeneration (AMD) and retinitis pigmentosa (RP) there has been little hope for maintaining vision.
There are presently no cures for these debilitating diseases, and, at best, current treatments only slow the disease progression.
The overall social and economic impact of AMD and RP is immense and the importance of treating blindness is profound as this is a problem of significant scope and breadth.
Advanced macular degeneration and retinitis pigmentosa are both diseases that degrade vision in patients and eventually will lead to blindness.
These devices apply an electric current pulse to stimulate the neurons of the visual system which is inherently hindered by a lack of spatial selectivity.
Electrical current spread leads to imprecise nerve stimulation and limits the ability of the neuroprosthesis to restore function.
The limitation of spatial selectivity is based on fundamental physical principles of electrical stimulation.
The technology is further limited by the fact that physical contact is required with tissue, which can lead to damage over time.
Implantation of a complex powered device in very close proximity to sensitive neural tissue forms a significant drawback to this approach, making it impossible to update the technology without further risky surgeries.
Electrical stimulation represents a major challenge in developing implantable devices with long-term system performance while reducing their overall size.
Since no micro-cables are required to be attached to the device, and its overall form and edges are rounded, the device is not expected to stress the retina during chronic implantation.
Electrical stimulation, as described in the above devices and patents, is limited since the spread of electricity does not allow separate or independent stimulation of individual retinal nerve cells or even small-enough groups of nerve cells.
Electrical stimulation thus greatly limits the number of separately stimulated sites that are possible.
Additionally, the electrical-stimulation approach will require implantation of a powered (e.g., an electrically powered) device, which has significant, difficult issues associated with obtaining power into the eye and using the power by devices in the eye.
This area may have some potential, however it will require significant development work, it involves injecting a virus into nerve tissue (which may have significant side effects and FDA-approval issues), and the virus is only partially taken up by nerve cells.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method and ocular implant for transmission of nerve-stimulation light
  • Method and ocular implant for transmission of nerve-stimulation light
  • Method and ocular implant for transmission of nerve-stimulation light

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0045]Although the following detailed description contains many specifics for the purpose of illustration, a person of ordinary skill in the art will appreciate that many variations and alterations to the following details are within the scope of the invention. Accordingly, the following preferred embodiments of the invention are set forth without any loss of generality to, and without imposing limitations upon the claimed invention. Further, in the following detailed description of the preferred embodiments, reference is made to the accompanying drawings that form a part hereof, and in which are shown by way of illustration specific embodiments in which the invention may be practiced. It is understood that other embodiments may be utilized and structural changes may be made without departing from the scope of the present invention.

[0046]The leading digit(s) of reference numbers appearing in the Figures generally corresponds to the Figure number in which that component is first intr...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

An improved prosthesis and method for stimulating vision nerves to obtain a vision sensation that is useful for the patient that has lost vision due to age-related macular degeneration (AMD) and retinitis pigmentosa (RP) and other diseases. The present invention utilizes infrared light to cause action potentials in the retinal nerves similar to those which result from rods and cones stimulated by visible light in healthy retinas. In some embodiments, the invention provides a pathway or “image pipe” for transmitting a stimulation pattern of infrared light from an external stimulator array through the eye and focusing the stimulation pattern of infrared light on the retina, especially the fovea. Some embodiments provide improved resolution down to a group of nerves, or even the individual nerve level, with sufficient energy density so as to cause a desired action potential.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a divisional of U.S. patent application Ser. No. 13 / 204,610 filed Aug. 5, 2011, titled “Ocular Implant and Method for Transmission of Nerve-Stimulation Light” (to issue as U.S. Pat. No. 8,709,078 on Apr. 29, 2014), which claims priority benefit under 35 U.S.C. §119(e) of U.S. Provisional Patent Application No. 61 / 514,894 filed Aug. 3, 2011, titled “Sight-Restoring Visual Prosthetic and Method Using Infrared Nerve-Stimulation Light” (Attorney Docket 5032.067PV1), both of which are incorporated herein by reference in their entirety.[0002]This invention is related to the following prior applications and patents:U.S. Provisional Patent Application No. 60 / 715,884 filed Sep. 9, 2005, titled “Apparatus and Method for Optical Stimulation of Nerves” (Attorney Docket 5032.009PV1);U.S. patent application Ser. No. 11 / 257,793 filed Oct. 24, 2005, titled “Apparatus for Optical Stimulation of Nerves and Other Animal Tissue” (now U.S....

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61N5/06
CPCA61N5/0601A61N2005/0659A61N2005/0643A61F2/14A61N5/0622
Inventor FRIEND, MICHAEL E.HU, YONGDAN
Owner LOCKHEED MARTIN CORP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products