Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Catheter and guide tube for intracerebral application

a guide tube and intracerebral technology, applied in the direction of catheters, applications, drug compositions, etc., can solve the problems of reducing the effectiveness of treatment, significant morbidity or treatment failure, and the number of difficulties encountered in such neurosurgical procedures, and achieve the effect of optimizing the placement of the catheter

Inactive Publication Date: 2011-11-17
RENISHAW (IRELAND) LTD
View PDF10 Cites 34 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0009]The present invention seeks to optimize the placement of the catheter whilst minimizing the trauma to the brain by utilizing small diameter catheter tubing.

Problems solved by technology

A number of difficulties are encountered in such neurosurgical procedures.
Sub-optimal placement of the instrument being inserted may lead to significant morbidity or treatment failure.
For such a small target sub-optimal placement of as little as 1 mm will not only reduce the effectiveness of the treatment, but may also induce unwanted side affects such as weakness, altered sensation, worsened speech and double vision.
However, functional neurosurgical targets are often difficult or impossible to visualize on diagnostic images, and so that actual position may be need to be inferred with the reference to visible landmarks in the brain and using a standard atlas of the brain to assist the process.
Other reasons for sub-optimal placement may result from patient movement during image acquisition, or geometric distortion of imaging which can be intrinsic to the images method.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Catheter and guide tube for intracerebral application
  • Catheter and guide tube for intracerebral application
  • Catheter and guide tube for intracerebral application

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0038]FIGS. 1, 2 and 3 show a catheter 1 according to the present invention. The catheter 1 includes a length of fine tubing 2, the outer diameter which is no more than 1 mm, and most preferably no greater than 0.7 mm. It is even more preferred that the outer diameter be no more than 0.5 mm. In this instance, the catheter tubing 2 is constructed from polyurethane plastic and preferably from carbothane 55 DB20 (Thermedics Polymer Products, Woburn Mass., USA). The fine tubing 2 is linked to a length of connector tubing 3 having an outer diameter of about 2 mm, via a hub 4. The connector tubing 3 is, in this case, made from polyurethane plastic, such as carbothane 85AB20, although other materials could also be used.

[0039]The hub 4 in this case is also constructed using polyurethane, such as carbothane 72 DB20. Again, other materials may also be appropriate.

[0040]The fine tubing 2 is intended to be inserted into the brain of a patient, whereas the connector tubing 3 is intended to be co...

example 2

[0044]The insertion of the catheter will now be described. Firstly, a stereotactic frame is attached to the patient's skull and the position of the intracranial target is identified by imaging the patient wearing the stereotactic frame and defining the position of the target as three dimensional co-ordinates. This step is explained in more detail in the introduction to this patent specification and is a standard technique within the field of neurosurgery.

[0045]Once the target has been defined, a stereoguide is used which is set to the target coordinates. An appropriately sized guide tube having an internal diameter of no more that 1 mm is directed into the brain in the direction of the target. The guide tube is arranged with a head at one end, which, once inserted, can be attached to the patient's skull, for example by being bonded into a burrhole in the skull using an acrylic cement.

[0046]Before insertion, the guide tube is cut to a length short of the target, and sufficiently shor...

example 3

[0050]In an alternative insertion technique, a number of phases or steps are taken which are shown in FIGS. 4 to 7. As will be appreciated, small diameter catheters have a tendency to drift off the planned trajectory during insertion as a result of the flexibility inherent in a small diameter instrument. Since neurosurgical targets are often deeply situated, typically 70-80 mm from the surface of the skull, and sometimes as much as 100 mm from the skull surface, the catheter must normally be very rigid, and therefore of a larger diameter.

[0051]Examples of possible targets include parts of the mesencephalon including the subthalamic nucleus, the substantia nigra and the pedunculor-pontine nucleus. This is a particularly critical region of the brain, where it is important to minimize trauma from the passage of an instrument, which is typically situated about 70-80 mm from the skull surface and contained within a volume which has a height of approximately 20-25 mm.

[0052]To facilitate i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A catheter for use in neurosurgery, and a method of positioning neurosurgical apparatus. The catheter has a fine tube arranged for insertion into the brain parenchyma of a patient with an external diameter of not more than 1.0 mm. The catheter and method may be used in stereotactically targeting treatment of abnormalities of brain function, and for the infusion of therapeutic agents directly into the brain parenchyma. This is advantageous when a therapeutic agent would have widespread unwanted effects which could be avoided by confining the delivery to the malfunctioning or damaged brain tissue.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This patent application is a Continuation of application Ser. No. 10 / 505,240, filed Feb. 22, 2005, which is a National Phase filing of PCT / GB03 / 01030, filed Mar. 11, 2003, which claims the benefit of priority of Great Britain Patent Application No. 0205772.7, filed Mar. 12, 2002. The disclosures of the prior applications are hereby incorporated by reference herein in their entirety.TECHNICAL FIELD[0002]The present invention relates to apparatus for use in neurosurgery, and to a method of positioning neurosurgical apparatus. The apparatus and method are particularly useful in stereotactically targeting treatment of abnormalities of brain function, and for the infusion of therapeutic agents directly into the brain parenchyma. This would be particularly useful when a therapeutic agent given systemically will have widespread unwanted side effects which would be avoided by confining the delivery to the malfunctioning or damaged brain tissue.BA...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61M5/142A61B19/00A61M1/00A61M25/00A61M25/02A61M25/08
CPCA61B19/201A61M25/00A61M25/02A61M39/0247A61M2210/0693A61M2025/0233A61M2039/025A61M2039/0273A61M2039/0282A61M2025/0042A61B2090/103A61B90/11A61P25/28A61P35/00A61P9/10
Inventor GILL, STEVEN STREATFILED
Owner RENISHAW (IRELAND) LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com