Temperature sensitive state-changing hydrogel composition and method for preparation
a technology of hydrogel and temperature sensitive state, applied in the direction of instruments, aerosol delivery, biocide, etc., can solve the problems of affecting the speed and quantity of drug delivery, the relative long time it takes for the medicine to penetrate into the skin, and the limitations of hydrogel in the form of gel
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[0052] Mix glycerine 170 g, Carrageenan 6 g and Locastgum 20 g at room temperature and stir in a 3 liter heatable container. Add to the mixture solution glycerine 30 g, metilparaben 0.8 g, propileparaben 0.3 g. Add 740 g of deionized water and heat the solution to 85° C. This will be the gel solution.
[0053] While maintaining the temperature at 85° C., add sequentially aloe extraction 20 g, collagen 5 g, imidazolidinylurea 2 g, twin80 1.5 g, and chitosan 3.7 g to the gel solution. This is the hydrogel composition. FIG. 1 shows the viscosity of the above hydrogel composition measured at various temperatures. As it is shown in FIG. 1, the hydrogel composition decreases its viscosity when the temperature increases and transforms to liquid state.
[0054] Hydrogel sheet can be produced by adding a rayon textile as a wick to this hydrogel composition at the temperature of 80° C. and then cooling it. This will be used to release beauty care ingredients to the skin.
[0055] Generally, when hy...
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