Benazepril hydrochloride dropping balls and their production

Abstract

A dripping pill of benazepril hydrochloride for treating hypertension and heart failure is prepared from benazepril hydrochloride and matrix. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a benazepril hydrochloride drop pill prepared from benazepril hydrochloride (Benazepril Hydrochloride) and a drop pill base. Background technique [0002] Hypertension is one of the most common cardiovascular diseases in the world today and the leading cause of death and disability in adults. Due to the improvement of people's living standards and the increasingly tense job competition, the number of people suffering from high blood pressure has increased greatly. The prevalence of hypertension in my country has increased significantly. According to statistics in China, the incidence of hypertension among people aged 35 to 74 in China is as high as 27%, and the number of patients is close to 130 million. , and with an annual growth rate of more than 300 million people, my country has become the country with the most serious hypertension hazards in the world. Hyperte...

AI Technical Summary

Problems solved by technology

[0015] Dissolution rate: get the sample of embodiment 1, according to the dissolution detection method (the characteristic that " Chinese Pharmacopoeia 2000 art technology has, makes this class oral preparation exist disintegration time long, slow onset, the disadvantages such as low bioavailability , thereby affecting the full play of the efficacy of the drug

It is also difficult to accommodate patients who have difficulty swallowing