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Self-reference, self-correlation and self-adaptive interference balancing method of evoked potential single extracted

A technology of induced potential and interference cancellation, applied in the field of medical equipment technology and biomedical engineering, it can solve the problems of changes, can not meet the needs of modern medical development, and the accuracy of results is not high, and achieve the effect of precise indicators

Inactive Publication Date: 2007-05-02
CHONGQING MEDICAL UNIVERSITY
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Problems solved by technology

The shortcomings of this theory are: (i) clinical practice has proved that the amplitude and latency of EP produced by each stimulus may vary, especially in patients; (ii) background signals, including spontaneous EEG (S-EEG) and 50Hz Interference, etc. are not noise with a mean value of 0
Especially when N=N i When the times BG(t) can be eliminated, N i +1 time will cause huge background signal BG to drown EP
From this point of view, the accuracy of the results obtained by the traditional evoked potential extraction method is not high, and it is increasingly unable to meet the development needs of modern medicine.

Method used

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  • Self-reference, self-correlation and self-adaptive interference balancing method of evoked potential single extracted
  • Self-reference, self-correlation and self-adaptive interference balancing method of evoked potential single extracted
  • Self-reference, self-correlation and self-adaptive interference balancing method of evoked potential single extracted

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specific Embodiment

[0037] Specific embodiments Single extraction of human visual evoked potential (VEP)

[0038] Single extraction steps for VEP:

[0039] (1) Obtained from the reference signal

[0040] Instrument: The visual electrophysiological examination system adopts the BIO2000 visual electrophysiological examination system produced by Chongqing Beiao Electronic Instrument Company.

[0041] The block diagram of the system is shown in Figure 1. The equipment is initialized, the subject lies supine, wears goggles, cleans the scalp where the electrodes are placed with anhydrous alcohol, coats the surface of the electrodes with a special conductive paste, fastens the two signal electrodes on the scalp with elastic bands, and fixes the reference electrode with medical adhesive tape. Sampling frequency: 2kHz; acquire 2 minutes of self-reference signal. The schematic diagram of the electrode configuration is shown in Figure 2, and the electrodes used are as follows: silver / silver chloride disc...

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Abstract

A self-reference, self-correlative and self-adaptive method for canceling the interference in extracting the evoked potential (EP) includes such steps as using a single electrode to take the self-reference signals for a long time, inputting the self-reference signals and comprehensive signals to the amplifier of electrobiologic examine system, amplifying, A / D conversion to obtain digital signals, and processing by special software (including self-reference analysis, calculating cancel factor W and canceling interference) to obtain EP, and calculating EP parameters.

Description

technical field [0001] The invention relates to a medical equipment technology and a biomedical engineering technology, and especially designs a self-reference autocorrelation self-adaptive interference cancellation method for a single extraction of evoked potentials. Background technique [0002] Evoked potential (EP: Evoked potential) is also called evoked brain potential (EBP: Evoked brainpotential), which is relative to spontaneous brain potential (SBP: Spontaneous brain potential). Evoked potentials include: (1) somatosensory evoked potentials, (2) visual evoked potentials, (3) auditory evoked potentials, (4) cognitive potentials, (5) olfactory evoked potentials, and (6) taste evoked potentials. Evoked potentials can be used to help diagnose sensory (visual, auditory, and somatosensory, etc.) system disorders, and to study development and aging. Studies have pointed out that before histological changes, patients with dementia (such as AD: Alzheimer's disease) have EP c...

Claims

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Application Information

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IPC IPC(8): A61B5/04A61B5/0476A61B5/0496G06F19/00
Inventor 谢正祥谢丹枚马厚勋钟雪飞王志芳
Owner CHONGQING MEDICAL UNIVERSITY
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