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Orally administered cervus and cucumis polypeptide composition and preparation method thereof

A composition and deer bone technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of waste, not suitable for oral administration, protein and polypeptide discarding, etc.

Active Publication Date: 2006-12-27
哈尔滨誉衡制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to solve the problems that most of the proteins and polypeptides above 10KD are discarded in the preparation process of the existing velvet melon polypeptide composition, the waste is serious, and the existing velvet melon polypeptide composition is not suitable for oral administration and the oral curative effect is poor. A kind of oral deer melon polypeptide composition and its preparation method provided

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0004] Specific Embodiment 1: In this embodiment, the oral deer melon polypeptide composition is made of 5 to 95 parts of polypeptide and 5 to 95 parts of excipients according to the ratio of parts by weight, wherein the polypeptide is deer bone polypeptide and melon seed polypeptide, and deer bone polypeptide and melon The weight ratio of the seed polypeptide is 4:1-1:4, and the molecular weight of the deer bone polypeptide and the melon seed polypeptide is ≤6KD.

specific Embodiment approach 2

[0005] Specific embodiment two: the difference between this embodiment and specific embodiment one is: the excipient consists of licorice, sucrose, simple syrup, sodium saccharin, sodium carboxymethylcellulose, dextrin, Tween-80, stearic acid One or more of magnesium, sodium carboxymethyl starch, hydroxypropyl cellulose, calcium hydrogen phosphate, and starch. Others are the same as the first embodiment.

specific Embodiment approach 3

[0006] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is that the excipient is composed of one or more of licorice, sucrose, and simple syrup. Others are the same as the first or second embodiment.

[0007] This embodiment is made into the Lugua polypeptide oral liquid.

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Abstract

The invention relates to a Chinese oral medicinal composition and its preparation, wherein the composition comprises 5-95 parts of polypeptides and 5-95 parts of excipient, the polypeptides include deer bone polypeptide and sweet melon seed polypeptide by a weight ratio of 4:1-1:4. And the making process comprises the steps of making deer bone polypeptide extract, makingsweet melon seeds polypeptide extract, and preparing polypeptides oral composition.

Description

technical field [0001] The invention relates to an oral medicine and a preparation method thereof. Background technique [0002] At present, there is too much protein loss in the preparation process of the deer melon polypeptide composition, such as patent CN1579542A (application number is 200410013602.7) and CN1742778A (application number is 200510108157.7), most of the proteins and polypeptides with molecular weight above 10KD are discarded during the preparation process; and , most of the existing Lugua polypeptide compositions are injections, which are not suitable for oral administration and have poor oral efficacy. Contents of the invention [0003] The purpose of the present invention is to solve the problems that most of the proteins and polypeptides above 10KD are discarded in the preparation process of the existing velvet melon polypeptide composition, the waste is serious, and the existing velvet melon polypeptide composition is not suitable for oral administrat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/42A61K38/17A61P19/02A61P29/00C12P21/00A61K35/32
Inventor 徐俊王东绪何利群王禹
Owner 哈尔滨誉衡制药有限公司
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