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Compound paracetamol injection for animal and preparation method thereof

A paracetamol and injection technology, which can be applied to non-active ingredients medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc. Effect

Inactive Publication Date: 2006-12-20
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For decades, doxycycline and other antibiotics have been listed as the first-choice drugs for treating high fever in pigs, but due to long-term and repeated use of antibiotics, pathogenic microorganisms have developed resistance to drugs, and drug residues in animal products affect their quality.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A compound acetaminophen injection for animals is prepared by the following method:

[0018] (1) Take 25 grams of propylene glycol and add 35 grams of water for injection, heat to 60-70 ° C, add 1.2 grams of acetaminophen, stir to dissolve; (2) add 1.5 grams of antipyrine into 40 grams of water for injection, stir Dissolving; (3) merging the solution made by step (1) and step (2), adding 1.5 grams of benzyl alcohol and stirring evenly, adding 1.5 grams of activated carbon and stirring, filtering, the color of the medicinal solution is colorless or almost colorless clear liquid, The filtrate is added with water for injection to 1000 grams, and a kind of acetaminophen injection is made.

Embodiment 2

[0020] Veterinary compound acetaminophen injection is prepared by the following method:

[0021] (1) Take 20 grams of propylene glycol and add 30 grams of water for injection, heat to 60-70 ° C, add 0.5 grams of acetaminophen, stir to dissolve; (2) add 6 grams of antipyrine into 45 grams of water for injection, stir Dissolving; (3) merging the solution made by step (1) and step (2), adding 1 gram of benzyl alcohol and stirring evenly, adding 1 gram of activated carbon and stirring, filtering, adding water for injection to 1000 grams of the filtrate, promptly making a kind of Acetaminophen Injection.

Embodiment 3

[0023] Veterinary compound acetaminophen injection is prepared by the following method:

[0024] (1) Take 50 grams of propylene glycol and add 40 grams of water for injection, heat to 60-70 ° C, add 5 grams of acetaminophen, stir to dissolve; (2) add 1 gram of antipyrine to 35 grams of water for injection, stir Dissolving; (3) merging the solution made by step (1) and step (2), adding 10 grams of benzyl alcohol and stirring evenly, adding 5 grams of activated carbon and stirring, filtering, adding water for injection to 1000 grams of the filtrate, promptly making a kind of Acetaminophen Injection.

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PUM

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Abstract

The invention relates to an animal composite acetaminopher injection and relative preparation, wherein said preparation comprises: (1) using the methyl ethylene glycol at 20-50 deals and adding water at 30-40 deals, to be heated to 60-70Deg. C and adding methyl ethylene glycol at 0.5-5 deals, to be mixed and dissolved; (2) adding analgesine at 1-6 deals into the water at 35-45 deals, to be mixed and dissolved; (3) combining the solutions at steps (1) and (2), and adding benzoic alcohol at 1-10 deals to be mixed uniformly, and adding active carbon at 1-5 deals to be mixed and filtered, adding water into the filtered solution to 1000 deals. The invention can improve the cure effect, to cure the high fever and cold caused by variable bacteria and virus.

Description

technical field [0001] The invention relates to an antipyretic and analgesic pharmaceutical composition and a preparation method. Background technique [0002] Pigs can cause high fever due to various infectious diseases and non-infectious inflammations, which is one of the most common diseases in pig herds and seriously restricts the development of pig industry. For decades, doxycycline and other antibiotics have been listed as the first-choice drugs for treating high fever in pigs all over the world. However, due to long-term and repeated use of antibiotics, pathogenic microorganisms have developed resistance to drugs, and drug residues in animal products affect their quality. Contents of the invention [0003] The purpose of the present invention is to overcome the deficiencies in the prior art and provide a compound acetaminophen injection for animals. [0004] The second object of the present invention is to provide a method for preparing veterinary compound acetamin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4152A61K9/08A61K47/10A61P29/00A61K31/167
Inventor 王连民魏宗生耿强斌
Owner TIANJIN SHENGJI GRP CO LTD
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