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A medicine for treating ankylosing spondylitis and preparation method thereof

An ankylosing spondylitis and drug technology, applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc. The effect of not easy to recur and eradicating stubborn pain

Inactive Publication Date: 2006-12-13
李东华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment non-steroidal drugs, anti-gout drugs, steroidal anti-inflammatory immune drugs and non-steroidal anti-inflammatory agents used in the treatment can only improve the symptoms, but cannot control the progress of the disease; Though preparation has certain curative effect, side effect is big, has influence on liver and gonad, and toxicity is big, can not long-term medication (referring to Chinese Orthopedic Journal 1984,4 (3), page 133, article written by Guo Juling; Tripterygium twig tincture treats rheumatoid arthritis and ankylosing spondylitis); some other agents such as D-penicillamine, gold salt, etc. are also used to treat ankylosing spondylitis at home and abroad, but the therapeutic effect is very poor
[0006] Traditional Chinese medicine includes two kinds of medicine for external use and medicine for internal use. The medicine for external use treats the symptoms but not the root cause, and the effect is not good; the medicine for internal use has been studied more, such as "a kind of medicament for treating ankylosing spondylitis and its preparation method disclosed by the Chinese patent application number 99117885". ", a "Chinese medicine composition for treating ankylosing spondylitis combined with osteonecrosis" disclosed in application number 01139923.6, "a drug for treating rheumatoid arthritis and ankylosing spondylitis and its preparation method disclosed in application number 200310115978.4 ", the traditional Chinese medicine treatment effect disclosed in these patent documents for the treatment of ankylosing spondylitis is not ideal, can not treat both symptoms and root causes

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Embodiment 1: the oral preparation of medicine of the present invention:

[0062] a) Take by weighing each bulk drug according to the following weight formula:

[0063] 2g deer horn glue, 1.5g cinnamon, 1.5g white mustard seed, 1g ephedra, 5g rehmannia glutinosa, 3g citrus aurantium, 4g salvia miltiorrhiza, 4g citrus officinalis, 4g dog spine, 3.5g epimedium, 1g scorpion, 1g centipede, Dipsacus 4g, astragalus 4g, angelica 4g, spare;

[0064] b) decoct the medicine (except deer horn gum) in the weight ratio twice with water. , Deer antler glue melting.

Embodiment 2

[0065] Embodiment 2: the pill preparation of medicine of the present invention:

[0066] a) Take by weighing each bulk drug according to the following weight formula:

[0067] 2g of deer horn glue, 1g of cinnamon, 1g of white mustard seed, 1g of ephedra, 5g of rehmannia glutinosa, 2g of Citrus aurantium, 3g of salvia miltiorrhiza, 3g of Morinda officinalis, 3g of dog spine, 3g of epimedium, 1g of scorpion, 1g of centipede, 3g of diapsis, astragalus 3g, angelica 3g, spare;

[0068] b) decoct ephedra, angelica, morinda officinalis, rehmannia glutinosa, and dog ridge in the above raw materials with water to obtain a concentrated solution, add honey and deer horn glue to concentrate into ointment;

[0069] c) drying the medicines such as white mustard seed, citrus aurantium, cinnamon, astragalus, epimedium, scorpion, centipede, and diapsae in the above raw materials, and grind them into fine powder;

[0070] d) Knead the above-mentioned powder and the above-mentioned ointment ev...

Embodiment 3

[0071] Embodiment 3: the capsule preparation of medicine of the present invention:

[0072] a) Take by weighing each bulk drug according to the following weight formula:

[0073] Deer horn glue 2.5g, cinnamon 2g, white mustard seed 2g, ephedra 1.5g, rehmannia glutinosa 6g, citrus aurantium 4g, salvia miltiorrhiza 4.5g, Morinda officinalis 5g, dog spine 5g, epimedium 4.5g, scorpion 1.5g, centipede 1g, Dipsacus 4.5g, Astragalus 5g, Angelica 5g, spare;

[0074] b) The above-mentioned raw medicines are dried, ground, and packed into No. 0 capsules.

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PUM

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Abstract

The invention discloses a medicament for treating spondylitis, which is prepared mainly from deer horn gum, Cinnamomum cassia, Chinese ephedra, white mustard seed, buthus martensi karsch, centipede, root of red rooted saliva, bitter orange, morinda root, dipsacus root, east Asian tree fern rhizome, astragalus root and Chinese angelica root by a predetermined weight proportions. The medicament can be prepared into decoction, pills and capsules.

Description

technical field [0001] The invention relates to a medicine for treating ankylosing spondylitis and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Ankylosing spondylitis belongs to the category of rheumatism and is a kind of seronegative spondyloarthropathy. It refers to a chronic progressive lesion whose cause is not yet clear, mainly invading the spine, sacroiliac joints and hip joints. It is a chronic disease with main lesions. The lesions mainly involve the sacroiliac joints, causing spinal stiffness and fibrosis, resulting in bending, limited walking activities, and various degrees of damage to multiple organs such as eyes, lungs, cardiovascular, and kidneys. . Ankylosing spondylitis occurs frequently in young men, and the peak age of onset is around 20 years old. Its onset is insidious, the course of the disease is long, recurrent, harmful, and can cause spinal deformi...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P29/00A61P19/02A61K35/64A61K35/32A61K35/646A61K35/648
Inventor 李东华
Owner 李东华
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