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Anti-fertility raticide utilizing phosphinyloxy aziridine for deratization and prescription thereof

A phosphine aziridine and rodenticide technology, applied in the field of anti-fertility rodenticides, can solve the problems of not being able to fundamentally solve the problem of rodents, hemorrhagic convulsions of rodents, poor rodent control and other problems, so as to avoid poisonous substances. Diffusion and environmental pollution, less alertness and panic, the effect of safe rodent control work

Inactive Publication Date: 2006-12-13
BEIJING GUIQIANJIN MEDICAL TECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the society uses drugs to kill rodents: among them, the first generation of highly toxic rodenticides is low in safety for humans and animals, and it is easy to cause secondary poisoning; the second generation of anticoagulant rodenticides often leads to After eating, some rats have bleeding and convulsions, which can easily cause panic and alertness of the same kind, and cause the rats to refuse to eat such drugs, so the rodent control effect is not good.
In addition, according to literature reports, the direct poisoning effect of these two types of drugs will cause a regional "population vacuum", stimulate the rapid reproduction of residual rats, and make the number of rats rebound rapidly, recovering or even exceeding the original level. It can be seen that traditional rodenticides endanger Human health, it is difficult to guarantee, consolidate and expand the effect of rodent control, and cannot fundamentally solve the problem of rodent infestation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The granule feed containing 0.02% phosphine oxyaziridine was selected as the rodenticide, and ICR male mice were used as the research object, fed for 7 days, and the sperm count and sperm morphology were checked after mating with the female mice, and the sperm count was found to be significantly reduced. The motility of the surviving sperm was extremely poor, and the rate of sperm deformity was significantly increased. The result of the experiment was that the fatality rate was 20% to 30%, and the fertility rate was 0%.

Embodiment 2

[0020] The granule feed containing 0.1% phosphine oxyaziridine was selected as the rodent control drug, and ICR male mice were used as the research object, fed for 3 days, and the sperm count, sperm morphology and testicular pathological examination were performed after mating with the female mice, and the sperm count was found Significantly decreased, while the mobility of the surviving sperm was extremely poor, the rate of sperm deformity was significantly increased, and the pathological changes of the testis. The result of the experiment was that the fatality rate was 33% to 42%, and the fertility rate was 0%.

Embodiment 3

[0022] The granule feed containing 0.05% phosphine oxaziridine is selected as the rodenticide. Under laboratory conditions, female rats are used as research objects. After feeding for 7 days, they are mated with male rats. The embryonic mortality rate is 71.2%. The deformity rate was 80%.

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PUM

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Abstract

The invention discloses a kind of ant bearing mouse trap agent, its use and its formula to kill and control the mouse breed. It contains the phosphine oxide aziridine barren medicament, the dait agent and rop findings, the main element, phosphine oxide aziridine can cause gland hurt for female mouse, the sperm occur barrier, at the same time, hae outstanding breed toxicity for female mouse, and can pass through the embryo and latex to transmit to descendant, seriously affect the bearing ability of descendant mouse. The mouse trap can escape the secondary hazarded phenomenon that bring by the traditional mouse trap, at the same time, the mouse cannot appearance the drastic reaction, such as bleed and convulsion after take in the mouse trap solvent, cannot cause awake of mouse, even more appearance the quickly rebound phenomenon of mouse group number after population vacuum, thus, it is a kind of biology ant bearing mouse trap agent that is safe and efficient, can use long period.

Description

technical field [0001] The invention relates to an anti-fertility rodenticide for extermination of rats, in particular to an anti-fertility rodenticide for extermination of rats by using the sterile agent phosphine-oxaziridine. The present invention also relates to a rodenticide formulation mainly composed of the sterile agent phosphine-oxaziridine. Background technique [0002] Rats are listed as the first of the four pests, and their hazards can reduce agricultural grain production, destroy trees in forestry, and cause various accidents in industry. More importantly, they can spread a variety of infectious diseases and seriously threaten human health. At present, most of the society uses drugs to kill rodents: among them, the first generation of highly toxic rodenticides is low in safety for humans and animals, and it is easy to cause secondary poisoning; the second generation of anticoagulant rodenticides often leads to After eating, some rodents have hemorrhage and conv...

Claims

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Application Information

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IPC IPC(8): A01N57/32
Inventor 王爱平刘巍张子伯王英明
Owner BEIJING GUIQIANJIN MEDICAL TECH
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