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Application of medicinal composition contg. Astragalus mongholicus in preparing medicine for treating aspirin-resistance disease

A technology of aspirin and composition, which is applied in the field of application of drugs in the preparation of drugs for treating aspirin resistance, and can solve problems such as aspirin resistance

Inactive Publication Date: 2006-01-25
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to alleviate the phenomenon of aspirin resistance that occurs when cardiovascular and cerebrovascular patients use aspirin drugs to treat cardiovascular and cerebrovascular diseases, some scientific researchers are currently looking for drugs that can replace or alleviate the phenomenon of aspirin resistance. Some drugs are tested in order to find new uses of their drugs to solve the phenomenon of aspirin resistance caused by current aspirin use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Take 375g of astragalus, 100g of angelica, 100g of rehmannia glutinosa, 50g of peach kernel, 50g of red peony root, 50g of Chuanxiong, 50g of earthworm, 50g of aurantium citrus (stir-fried), 50g of notoginseng, 75g of salvia miltiorrhiza, 25g of licorice, 75g of safflower, 75g of achyranthes bidentata, and borneol 1.6g spare;

[0073] The above fourteen flavors, except safflower, ground borneol and dissolved in an appropriate amount of ethanol; the other twelve flavors such as astragalus are decocted twice, the first time is 2 hours, the second time is 1 hour, and the safflower is decocted in the second time. Add it while boiling, combine the decoction and filter, concentrate the filtrate to a relative density of 1.20 (40°C), add twice the amount of 90% ethanol, mix well, let stand for 12 hours, take the supernatant to recover ethanol, concentrate to a relative density of 1.30 (40°C), dry, crush, add sugar powder and ethanol to make granules, dry, spray with borneol eth...

Embodiment 2

[0075] Take 150g of astragalus, 50g of angelica, 50g of rehmannia, 100g of peach kernel, 25g of red peony root, 25g of Chuanxiong, 25g of earthworm, 25g of citrus aurantium (stir-fried), 25g of notoginseng, 30g of salvia miltiorrhiza, 10g of licorice, 30g of safflower, 30g of achyranthes bidentata, borneol 0.8g, tableted according to conventional tablet preparation methods, to obtain. .

Embodiment 3

[0077] Take 700g of astragalus, 200g of angelica, 50g of rehmannia glutinosa, 100g of peach kernel, 100g of red peony root, 25g of Chuanxiong, 100g of earthworm, 100g of citrus aurantium (stir-fried), 100g of notoginseng, 150g of salvia miltiorrhiza, 50g of licorice, 150g of safflower, 150g of achyranthes bidentata, borneol 3.2g, the Chinese medicine preparation of the present invention is made by the preparation process of embodiment 1, is packed into the electuary of 25g one bag, obtains final product.

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PUM

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Abstract

A Chinese medicine for treating the aspirin-resistant cardiovascular disease is prepared from 14 Chinese-medicinal materials including astragalus root, Chinese angelica root, rehmannia root, peach kernel, etc.

Description

technical field [0001] The invention relates to the field of medicine, in particular, the invention relates to the application of a medicine in the preparation of medicine for treating aspirin resistance. Background technique [0002] Aspirin, also known as aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth study of prostaglandins, a new understanding of aspirin has emerged: in addition to traditionally used for antipyretic, analgesic, and anti-inflammatory clinically, it is also used for anti-platelet aggregation and so on. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspirin is...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K36/00A61K9/00A61P9/10
Inventor 李永强郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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