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Medicinal composition for treating acute, chronic pharyngolaryngitis and its preparation method

A chronic pharyngitis and composition technology, applied in the field of traditional Chinese medicine, can solve the problems that syrup and granules do not provide control efficacy indicators, cannot guarantee the exact curative effect of medicines, and weaken prescriptions for clearing away heat and detoxification, so as to facilitate large-scale promotion, enhance heat-clearing and detoxification, The effect of rigorous structure

Inactive Publication Date: 2005-03-09
成都三明药物研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation process is simple. Although the medicinal flavor of nourishing yin and moistening dryness is added to the raw material prescription, the efficacy of clearing away heat and detoxifying is weakened.
Moreover, the syrup and granules do not provide control drug efficacy indicators, and the controllability is poor, which makes the drug have great shortcomings in use, and the exact curative effect of the drug cannot be guaranteed.

Method used

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  • Medicinal composition for treating acute, chronic pharyngolaryngitis and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 medicine oral liquid of the present invention

[0025] 1. Weigh raw materials according to the prescription: Shegan 700g, Scutellaria baicalensis 200g, Bellflower 300g

[0026] Excipients: ethyl p-hydroxybenzoate 1.0g, made into 1000ml;

[0027] 2. Process:

[0028] a. Shoot 8 times the amount of water and extract three times, each time for 1 hour, filter, and collect the filtrate for later use;

[0029] b. Platycodon grandiflorum and baicalensis were boiled and extracted three times with 8 times the amount, each time for 1 hour, filtered, and the filtrate was collected for later use;

[0030] c. The above filtrates are mixed and concentrated to a relative density of 1.16-1.19 (80°C);

[0031] d. Add 95% v / v ethanol to the concentrated solution to make the alcohol content reach 60% v / v, let stand, and filter;

[0032] e, collect the filtrate and reclaim ethanol under reduced pressure;

[0033] f. Dissolve ethyl p-hydroxybenzoate with an appropriate amo...

Embodiment 2

[0037] Embodiment 2 pharmaceutical capsules of the present invention

[0038] 1. Weigh raw materials according to the prescription: Shegan 500g, Scutellaria baicalensis 500g, Campanulaceae 500g

[0039] Excipients: appropriate amount of calcium hydrogen phosphate, starch, magnesium stearate

[0040] 2. Process:

[0041] a. Extraction: add the above-mentioned three flavors (Scutellaria baicalensis is added after boiling water), add 8 times the amount of water, boil and extract three times, each time for 1 hour, filter, and collect the filtrate for later use;

[0042] b. Concentration: Combine the filtrate, concentrate the filtrate to a relative density of 1.20-1.25 (60°C), stir while it is hot, slowly add three times the amount of ethanol, stir well, let stand for 24 hours, filter, collect the filtrate, and use 70% v for the residue / v ethanol washed twice, combined, filtered, combined with the above filtrate;

[0043] c. Drying, crushing and subpackaging: recover ethanol un...

Embodiment 3

[0045] Embodiment 3 medicine buccal tablet of the present invention

[0046] 1. Weigh raw materials according to the prescription: Shegan 500g, Scutellaria baicalensis 500g, Campanulaceae 500g

[0047] Excipients: powdered sugar, dextrin, appropriate amount of essence

[0048] 2. Process:

[0049]a. Extraction: add the above-mentioned three flavors (Scutellaria baicalensis is added after boiling water), add 8 times the amount of water, boil and extract three times, each time for 1 hour, filter in stages, and collect the filtrate for later use;

[0050] b. Concentration: Combine the filtrate, concentrate the filtrate to a relative density of 1.20-1.25 (60°C), stir while it is hot, slowly add three times the amount of ethanol, stir well, let stand for 24 hours, filter, collect the filtrate, and use 70% v for the residue Wash twice with / v ethanol, combine, filter, combine with the above-mentioned filtrate, concentrate at low temperature to an extract with a density of 1.32 (80...

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Abstract

The invention provides a medicinal composition for treating acute and chronic pharyngolaryngitis, which is prepared by Chinese medicine belamcanda rhizome, baicalin, ballonflower. The Chinese medicine preparation contains baicalin whose content in per unit is in a range of 20 mg to 120 mg. The invention also provides preparation method of the medicinal composition. The medicinal composition has good effect for treating the acute and chronic pharyngolaryngitis. And the medicinal composition has simple and reasonable prescripton, and can be prepared easily and in low cost, and can be controlled accurately.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating acute and chronic pharyngitis and a preparation method thereof. Specifically, it relates to a pharmaceutical composition prepared from traditional Chinese medicines Shegan, Scutellaria baicalensis and Platycodon grandiflorum as raw materials and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] Due to the increasingly serious environmental pollution, especially air pollution such as automobile exhaust, etc., can easily cause various diseases of people's upper respiratory tract infection, such as acute and chronic pharyngitis, which seriously affects people's health. [0003] Acute pharyngitis (acute pharyngitis) refers to the acute inflammation of pharyngeal mucosa, submucosal tissue and lymphoid tissue, mostly caused by viruses, bacteria or physical and chemical factors. Its cause of disease is mainly virus infection and...

Claims

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Application Information

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IPC IPC(8): A61J3/00A61P11/04
Inventor 阳向波张媛
Owner 成都三明药物研究所
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