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Application of red sage root and its prepatation in making medicine for treating aspirin resistance blood vessel disease

A technology for cardiovascular and cerebrovascular diseases and aspirin, which is applied in the field of medicine and can solve problems such as unseen Danshen preparations

Inactive Publication Date: 2005-03-09
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, research work has found that Compound Danshen Dripping Pills also has anti-atherosclerosis, lowering blood lipids, and anti-fibrosis effects of chronic liver diseases, but so far there is no relevant Danshen preparation, especially the effect of Compound Danshen Dripping Pills on aspirin resistance exact report of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Embodiment 1: the preparation method of Danhong injection

[0091] 1. Take 750g of Danshen, 250g of safflower, and 7g of sodium chloride for injection;

[0092] 2. The above two herbs, Danshen soaked twice in dilute ethanol, 1 hour each time, filtered, and the filtrate was used for later use; the dregs were mixed with safflower, soaked twice in water, 1 hour each time, filtered, and the filtrate was combined , concentrated to a clear paste with a relative density of 1.10-1.20 (65°C), add sodium chloride for injection to make it isotonic, adjust the pH value to 6-7, filter, refrigerate for 24 hours, add water for injection to the specified amount, filter After drying, potting, and sterilizing, it is ready.

Embodiment 2

[0093] Embodiment 2: the preparation method of strong Naoxinkang capsule

[0094] 1. Take 1500g of Salvia miltiorrhiza, 1500g of the extract of Amygdalus miltiorrhiza, and 125g of royal jelly for later use;

[0095] 2. For the above three flavors, take 75% of salvia miltiorrhiza, crush it into fine powder; crush the rest of salvia miltiorrhiza into coarse powder, add water to decoct three times, the first and second time each for 2 hours, and the third time for 3 hours, combine the decoction, filter, and reduce the filtrate Concentrate under pressure to a thick paste with a relative density of 1.30-1.32 (70°C), dry under reduced pressure, grind into fine powder, mix with the above fine powder, make granules, and dry; after the royal jelly is freeze-dried into fine powder, mix with the above granules Mix well, put into capsules, and get ready.

Embodiment 3

[0096] Embodiment 3: the preparation method of Tongxinshu capsule

[0097] 1. Take 250g of seabuckthorn flavonoids, 20g of salvia miltiorrhiza extract, 10g of Chuanxiong, and 20g of talcum powder for later use;

[0098] 2. The above three flavors, Ligusticum chuanxiong are crushed into fine powder; mix seabuckthorn flavonoids with fine powder of Ligusticum chuanxiong and Danshen extract, add talcum powder, mix well, put into capsules, and get ready.

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PUM

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Abstract

An application of red sage root and its extract in preparing the medicines in the form of dripping pill or tablet for treating the aspirin-resistant cardiovascular and cerebrovascular diseases is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of salvia miltiorrhiza and its preparations in the preparation of medicines for treating aspirin-resistant cardiovascular diseases. Background technique [0002] Aspirin is a non-steroidal anti-inflammatory drug, which is an effective antipyretic, analgesic and anti-inflammatory drug. Its mechanism of action is to inhibit the synthesis of prostaglandins. The most common side effects of this drug are gastrointestinal reactions, such as loss of appetite, ulcers, Even perforation; allergic reaction; acute renal failure, chronic interstitial nephritis, etc. With the in-depth research on aspirin, the indications of aspirin have also expanded from the treatment of fever, mild to moderate headache, toothache, neuralgia, joint pain, muscle pain and dysmenorrhea, rheumatism, etc. to cerebral arteriosclerosis, coronary heart disease, Treatment ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P9/00A61P9/10A61P43/00
Inventor 吴廼峰郭治昕郑军张雷浦奎赵娜
Owner TIANJIN TASLY PHARMA CO LTD
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