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Chinese traditional medicine for treating bradycardia

A bradycardia, traditional Chinese medicine technology, applied in drug combinations, pharmaceutical formulations, cardiovascular system diseases, etc., can solve problems such as no effective treatment drugs, slow heart rate, difficulty urinating, etc.

Inactive Publication Date: 2004-12-29
HENGXING PHARMA INST HEFEI
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  • Summary
  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

Clinically, the drugs used to increase the heart rate are mainly atropines, which have a quick onset and obvious effect, but the duration is short, and there are adverse reactions such as dry mouth, hot face, and dysuria in elderly men.
Antiarrhythmic drugs commonly used in clinical practice include amiodarone, digoxin and other cardiotonic drugs, but after taking them, the heart rate often slows down significantly.
Especially for the bradycardia caused by amiodarone, no effective treatment drug has been found in the world so far (atropine is invalid)
Therefore, it is necessary to disable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] Now take the capsule as an example, and the non-limiting examples are described as follows.

[0019] 1. Take 40 parts of astragalus and 60 parts of aconite, mix them, add 10 times the amount of water and soak for 1-2 hours, then heat and reflux for 2-3 hours, and separate to obtain the water extract. The filter residue was refluxed with 8 times the amount of water for 2 hours and separated. The two water extracts are combined, dehydrated and concentrated to obtain an extract, and then dried to obtain an extract powder. About 21 parts of extract powder can be obtained per 100 parts of mixed raw medicinal materials. If the water extract is removed by alcohol precipitation, 15-18 parts of extract powder can be obtained.

[0020] Mix the extract powder with the auxiliary material micro-powder silica gel - dextrin and pack evenly. # Capsules, each containing about 0.4-0.45g, of which the active ingredient is equivalent to 1.3-1.4g of raw medicinal materials, taken three t...

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Abstract

The bradyrhythmia treating Chinese medicine is orally taken preparation obtained with astragalus root and aconite root as main material. Two types of pharmacodynamic bradyrhythmia model test, including amiodaronum rat and propranolol rat show that the bradyrhythmia treating Chinese medicine can raise the heart rate obviously and has no toxic side effect produced after being taken regularly.

Description

1. Technical field [0001] The invention relates to a medicinal composition for treating bradycardia, in particular to a traditional Chinese medicine for treating bradycardia prepared from plant Chinese herbal medicines. 2. Background technology [0002] Bradycardia is a systemic disease caused by multiple etiologies, mainly heart disease, mostly in the elderly. When the heart rate slows down to a certain level, the blood supply to various important organs decreases to varying degrees, and clinical symptoms such as dizziness, chest tightness, and fatigue often require surgery to install an artificial cardiac pacemaker. Clinically, the heart rate-increasing drugs are mainly atropines, which have quick onset and obvious effects, but last for a short time, and have adverse reactions such as dry mouth, hot face, and dysuria in elderly men. Clinically commonly used antiarrhythmic drugs include amiodarone, digoxin and other cardiotonic drugs, but they often slow down the heart rat...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61P9/06
Inventor 雷红金继曙魏伟陈敏珠
Owner HENGXING PHARMA INST HEFEI
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