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Medicine for treating dementia and preparing method thereof

A technology for drugs and dementia, applied in the field of medicine, can solve the problems of low curative effect, slow absorption and excretion, accumulation of poisoning and side effects, etc., and achieve the effects of low drug toxicity and side effects, reasonable prescription and definite curative effect.

Inactive Publication Date: 2004-12-08
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned drugs have a certain effect on improving the symptoms of dementia and have a certain curative effect clinically, the above-mentioned drugs are prone to accumulation poisoning and side effects due to slow absorption and excretion after long-term use, and cannot fundamentally block dementia or vascular disease. With the progress of dementia, it is difficult to adapt to the needs of human beings to pursue health increasingly
And some traditional Chinese medicine preparations for treating senile dementia and vascular dementia, such as the Patent Invention Bulletin of the China Patent Office, disclosed a kind of title "a kind of medicine for treating senile dementia and its preparation method" on May 20, 1997, applying for No. 97116461.4, the patent application document with the publication number CN1181966A; the Patent Invention Bulletin of the China Patent Office on June 9, 1993 disclosed a patent application document named "The formula and preparation process of anti-brain failure capsule" with the application number 92114222.6 , in these traditional Chinese medicine preparations, the taste of the medicine used is more, it is difficult to control the quality of the medicine, and it is not suitable for industrialized large-scale production. In addition, the existing Chinese medicine preparations have low curative effect on improving the symptoms of dementia, and it is difficult to inhibit the progress of dementia.

Method used

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  • Medicine for treating dementia and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0095] Embodiment 1: the preparation of dropping pill

[0096] Take selected Chinese medicine raw materials with the following weights and go through screening, purification and crushing for later use:

[0097] Astragalus 16.7g, Salvia 16.7g, Chuanxiong 10g, Atractylodes 10g, Shichangpu 10g, Coptis 3.3g, Borneol 0.0667g;

[0098] Take astragalus and dandelion and add 10 times the amount of water, reflux and extract twice, 1.5 hours each time, filter the extract, and set aside; add 10 times the amount of water to Chuanxiong, Atractylodes atractylodes, and Shichangpu, extract the volatile oil with a volatile oil extractor for 8 hours, and use the volatile oil for later use. Filter out the water extract, add 10 times the amount of water to extract the dregs of the medicine for 1.5 hours, combine the water extract, filter and combine with the Astragalus miltiorrhiza extract and concentrate under reduced pressure to 1ml approximately equal to 1g crude drug, let cool, add 95% ethano...

Embodiment 2

[0101] Embodiment 2: the preparation of granule

[0102] Take selected Chinese medicine raw materials with the following weights and go through screening, purification and crushing for later use:

[0103] Astragalus 25.5g, Salvia miltiorrhiza 25.5g, Chuanxiong 15g, Atractylodes 15g, Shichangpu 15g, Coptis 7.5g, Borneol 0.8g;

[0104] Take astragalus and dandelion and add 14 times the amount of water, reflux and extract twice, each time for 3 hours, filter the extract, and set aside; add 12 times the amount of water to Chuanxiong, atractylodes, and calamus, extract the volatile oil with a volatile oil extractor for 12 hours, and use the volatile oil for later use. Filter out the water extract, add 12 times the amount of water to extract the dregs of the medicine for 3 hours, combine the water extract, filter and combine with the extract of Astragalus miltiorrhiza miltiorrhiza and concentrate under reduced pressure to 1ml, which is approximately equal to 1.5g of crude drug, let ...

Embodiment 3

[0107] Embodiment 3: the preparation of capsule

[0108] Take selected Chinese medicine raw materials with the following weights and go through screening, purification and crushing for later use:

[0109] Astragalus 8.5g, Salvia 8.5g, Chuanxiong 5g, Atractylodes 5g, Shichangpu 5g, Coptis 2g, Borneol 0.01g;

[0110] Take astragalus and dandelion and add 8 times the amount of water, reflux and extract twice, each time for 2 hours, filter the extract, and set aside; add 8 times the amount of water to Chuanxiong, Atractylodes atractylodes, and Shichangpu, extract the volatile oil with a volatile oil extractor for 4 hours, and use the volatile oil for later use. Filter out the water extract, extract the dregs with 10 times the amount of water for 2 hours, combine the water extract, filter and combine with the Astragalus miltiorrhiza extract and concentrate under reduced pressure to 1ml approximately equal to 0.5g crude drug, let cool, add 90% ethanol to make Alcohol concentration ...

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Abstract

A Chinese medicine for treating chronic dementia, sanile dementia, vanular dementia and AD is prepared from 7 Chinese-medicinal materials including astragalus root, red sage root, Chuan-xiong rhizome, borneol, etc. Its advantages are high curative effect and quickly taking its effect.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a medicine for treating dementia and a preparation method thereof. Background technique [0002] Dementia is a common geriatric disease, and it is also recognized as a refractory disease in the medical field today. According to the report of the World Health Organization, among the elderly over 65 years old, 10% of them have mental disorders, and 60% of them develop dementia, and With increasing age, the incidence of dementia showed a sharp upward trend. Dementia that occurs in old age can be divided into two categories: chronic and acute according to the speed of symptom development: Chronic dementia accounts for about 80% of old age dementia, also known as senile chronic brain syndrome. It includes senile dementia, vascular dementia, and mixed dementia in which the two coexist. In addition, there are some rare dementias, such as subacute spongiform encephalopathy, Parkinso...

Claims

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Application Information

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IPC IPC(8): A61P25/28
Inventor 颜德馨颜乾麟
Owner TIANJIN TASLY PHARMA CO LTD
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