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Method and apparatus for non-intrusive photoacoustics measurement to living body

A non-invasive, in vivo technology, applied in measuring devices, blood characterization devices, diagnostic recording/measurement, etc., can solve problems such as difficult to obtain photoacoustic signals and weak photoacoustic signals

Inactive Publication Date: 2004-05-05
TOSHIBA MEDICAL SYST CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] However, since the generated photoacoustic signal is very weak, it is difficult to obtain a photoacoustic signal with a good signal-to-noise ratio, which is necessary for measuring glucose concentration, even after using repeated measurements and signal averaging

Method used

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  • Method and apparatus for non-intrusive photoacoustics measurement to living body
  • Method and apparatus for non-intrusive photoacoustics measurement to living body

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Embodiment Construction

[0030] figure 1 It is a schematic diagram of a device for non-invasive measurement of living body information related to the first embodiment of the present invention. exist figure 1 , the light source unit 8 radiates one or more monochromatic light beams or light beams with a desired central wavelength and bandwidth. When two or more light beams are radiated from the light source unit 8 , they are multiplexed by the optical multiplexer / waveguide unit 9 . The light beam is then guided to the irradiation unit 10 via an optical waveguide forming part of the optical multiplexer / waveguide unit 9, and the light is irradiated from the irradiation unit 10 onto the measurement site of the patient 14, wherein the optical waveguide such as be optical fiber, optical thin-film waveguide, or free space. Also, the light source unit 8 generates a reference light signal 16 which is an electrical signal and is proportional to the intensity of each monochromatic light or light having a desir...

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Abstract

A method and apparatus for non-invasive measurement of living body information comprises a light source configured to generate light containing a specific wavelength component, an irradiation unit configured to irradiate a subject with the light, and at least one acoustic signal detection unit including piezoelectric devices formed of a piezoelectric single crystal containing lead titanate and configured to detect an acoustic signal which is generated due to the energy of the irradiation light absorbed by a specific substance present in or on a subject.

Description

technical field [0001] The present invention relates to methods and devices for the non-invasive measurement of at least one parameter of a sample using photoacoustic spectroscopy, such as the presence and / or concentration of one or more analytes, or for characterizing a tissue part of the human body. Physical and / or chemical constants. Background technique [0002] The analysis of a sample and the concentration measurement of its constituents is a common and important process in chemistry and biology. In particular, analysis of biological fluids such as blood, interstitial fluid, urine or saliva to determine the concentration of various components and determine pathology is important for the diagnosis and treatment of various diseases including diabetes and heart disease. Measurements of physical and / or chemical constants characterizing tissues are also useful in the diagnosis of various diseases such as tumors. A representative device for measuring the concentration of a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N29/00A61B5/00A61B5/145A61B5/1455A61B8/00G01N21/00G01N21/17G01N29/22G01N29/24G01N29/32
CPCG01N29/326G01N2291/015G01N21/1702A61B5/1455A61B5/0095A61B8/00G01N29/449A61B5/14532G01N29/22G01N2291/02466G01N29/2418A61B5/14
Inventor 金山省一逸見和弘奥马·S.·卡李尔斯坦尼斯劳·肯特
Owner TOSHIBA MEDICAL SYST CORP
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