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Soluble anti-inflammation, antibiotic and hemostatic gauze and method for making the same

The technology of a hemostatic gauze and a processing method is applied in the processing of soluble anti-inflammatory, hemostatic gauze, and the fields of the above-mentioned soluble anti-inflammatory, antibacterial, and hemostatic gauze, and can solve the problems of inconvenience of smearing or external application, secondary wound injury, long duration of drug effect, etc. To achieve the effect of timely healing and uniform efficacy

Inactive Publication Date: 2004-01-14
张博
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention overcomes the shortcomings of the existing sulfonamide topical ointment or powder medicines in the treatment of external wounds, the dosage is limited, the smearing or external application is inconvenient, and the wound is easy to bind with gauze after the wound scabs, causing secondary trauma of the wound. A kind of soluble anti-inflammatory, antibacterial and hemostatic gauze, the gauze will not cause secondary trauma to the wound, the drug is released evenly and continuously, the drug effect lasts for a long time, and can provide nutrients for the wound, and the wound heals quickly

Method used

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Examples

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Effect test

specific Embodiment approach 1

[0021] A soluble anti-inflammatory, antibacterial, hemostatic gauze made of silver sulfadiazine condensed on soluble fibers by amino acid.

specific Embodiment approach 2

[0022] A soluble anti-inflammatory, antibacterial, hemostatic gauze made of amino acid condensed sulfasalazine onto soluble fibers.

specific Embodiment approach 3

[0023] A kind of processing method of soluble anti-inflammation, antibacterial, hemostatic gauze, comprises following sequential steps:

[0024] (1) In the reaction tank, adding concentration is 100Kg of monochloroacetic acid ethanol solution of 60%, namely 95% ethanol 60Kg, monochloroacetic acid 40Kg; hours, shake dry;

[0025] (2) Add 85Kg and 15Kg amino acids in the reaction tank, add NaOH to adjust the pH value to 10, heat the gauze treated in step (1) to 80°C in 15% amino acid aqueous solution for 5 hours, and dry the gauze ;

[0026] (3) Add 75% ethanol aqueous solution 80Kg and NaOH32Kg in reaction tank, get NaOH saturated solution 112Kg, the gauze that step (2) is processed is soaked in above-mentioned NaOH saturated solution etherification reaction 4 hours at normal temperature, gauze is shaken dry, dry;

[0027] (4) adding hydrochloric acid dropwise to the gauze treated in step (3) in 95% ethanol aqueous solution to adjust the pH to 6 for neutralization, and dryin...

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Abstract

A soluble gauze with inflammation-relieving, antibacterial and staltic function is prepared through immersing the absorbent gauze in the solution of monochloroacetic acid, reaction of said gauze on amino acid, immersing in saturated solution of NaOH, etherifying reaction, putting the gauze in the aqueous solution of alcohol, dropping hydrochloric acid to regulate pH value to 5.4-7.6, washing, and reaction between treated gauze and sulfa drug. Its advantages are high effect to provide nutrients to wound and promote healing of wound, and durable action.

Description

Technical field [0001] The invention relates to a gauze for external application on wounds, in particular to a soluble anti-inflammatory, antibacterial and hemostatic gauze, and further relates to a processing method of the above-mentioned soluble anti-inflammatory, antibacterial and hemostatic gauze. Background technique [0002] Since the discovery of sulfonamides in 1935, they are the earliest synthetic chemotherapy drugs that are effective in the treatment of systemic infections. After the 1940s, the development of antibiotics and the emergence of synthetic quinolones in the 1970s partially replaced sulfa drugs. But because it still has unique advantages, it has good curative effect on certain infectious diseases (such as meningitis, plague), easy to use, stable properties, and low price. After combined use, most of them enhance their antibacterial efficacy and antibacterial range, and sulfonamides still have a certain status in clinical treatment. At present, there ar...

Claims

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Application Information

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IPC IPC(8): A61L15/44D06M13/342
Inventor 张博
Owner 张博
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