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Cattail pollen extract and preparation process and use thereof

A technology of extract and Puhuang, which is applied in the field of preparing medicine or food for preventing and treating myocardial ischemic cardiovascular disease

Inactive Publication Date: 2003-08-06
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

So far, there is no report on the prevention and treatment of myocardial ischemic cardiovascular disease with Puhuang extract

Method used

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  • Cattail pollen extract and preparation process and use thereof
  • Cattail pollen extract and preparation process and use thereof
  • Cattail pollen extract and preparation process and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Put 100 kg of Puhuang medicinal materials into the extraction tank, soak in 100 liters of 70% ethanol at room temperature for 24 hours, boil and extract 3 times with 800 liters of 70% ethanol at 90-100 ° C, each extraction time is 2 hours, and combine the 3 extractions liquid, concentrated to 50 liters, filtered, and the filtrate was adjusted to 100 liters with distilled water. Slowly pass through the adsorption column that 200 liters of ZTC-1 type macroporous resin (produced by Tianjin Zhengtiancheng Clarification Technology Co., Ltd.) is housed again, remove impurity with 1000 liters of distilled water rinses; Remove liquid, concentrate to 10 liters, slowly add 100 liters of 95% ethanol under stirring, after adding, let it stand for 12 hours, centrifuge to discard the precipitate, concentrate the supernatant to dryness, further dry and pulverize to obtain yellow powder The yellow extract is 1.8 kg, and the yield is 1.8% based on crude drug amount. Bioactivity assay ...

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PUM

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Abstract

The present invention relates to a cattail pollen extract, its preparation method and its application. Its preparation method includes the following steps: using aqueous ethyl alcohol to make thermalextraction of typha poller, and adopting macroporous resin adsorption chromatographic process to obtain the invented typha pollen extract whose total flavone content is up to 50%. The animal tests show that it can obviously reduce extent of myocardial ischemia after ligation of canine coronary artery, can reduce the range of myocardial ischemia, can obviously reduce infarct range and can obviously reduce myocardial oxygen consumption, etc. so that it can be used for preparing medicine or food for preventing and curing angio cardiopathy due to myocardial ischemia.

Description

Technical field: [0001] The invention relates to the technical field of medicine, and relates to an extract of Puhuang and a preparation method thereof and the use of the extract of Puhuang in preparing medicine or food for preventing and treating myocardial ischemic cardiovascular disease. Background technique: [0002] Cattail is a commonly used medicinal material, which comes from the pollen of Typha L. Typha angustifolia L., Typha angustata Bory et Chaub, Typha angustata Bory et Chaub, and T. latifolia L. of the family Typhaceae. Alias ​​cattail pollen, cattail yellow and so on. Its medicinal use has a long history, and was listed as top grade in "Shen Nong's Materia Medica" in the Han Dynasty. It has the effects of stopping bleeding, removing blood stasis and treating stranguria. For vomiting blood, epistaxis, hemoptysis, uterine bleeding, traumatic hemorrhage, amenorrhea and dredging menstruation, epigastric pain, tumbling and swelling pain, bloody stranguria and ast...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61P9/10C07D311/30C07H1/08C07H17/07
Inventor 陈万生邱彦关军殷学平王萍陶朝阳李铁军梁晶晶
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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