Visible light induced delayed lighting no-damage tumor imaging method and equipment

Abstract

The present invention discloses a tumor imaging method of nondamaging with delay lighting guided by visible light to the public incluing the steps as follows, preguiding in photosensitive reagent of porphrin and delay lighting reagent of active seralbumin and using visible light to shine the living body or tissue to guide the living body or tissue to create a delay lighting of inner source for a quite long period. The light receiving assembly will convert this lighting signal into electric signal which is converted into digital signal by analog / digital conversion and to process the digital signal for obtaining the structure image of living body or tissue. The device of this invention includes visible light ignition assembly, light receiving assembly, analog / digital convertor and computer.The present invention combines the advatnages of low interference in background of delay lighting, high resolving powder of optical image, used reagent with no chamical damage to livign body and focusing selection to tumor part together for obtaining high resolving power and clear image of tumor disease in the image diagnosis of biological medicine.

Description

(1) Technical field [0001] The invention relates to a medical imaging diagnosis technology of tumors, in particular to a method and a device for non-damaging tumor imaging by using delayed chemiluminescence induced by visible light. (2) Background technology [0002] Among the imaging technologies commonly used in medical imaging diagnosis at present, X-ray transmission imaging, X-ray tomography (CT), and nuclear magnetic resonance imaging all have a large degree of damage to human tissues, and X-ray tomography scanners, nuclear magnetic resonance imaging machines, etc. The cost of B-mode ultrasonic imaging is relatively expensive; B-mode ultrasonic imaging has basically no damage to the human body, and the cost is also low, but because the principle of B-mode ultrasonic imaging is tissue interface reflection imaging, it cannot achieve tomography, and the resolution is low (for simple structures) In vivo tissue, the best resolution is a few millimeters), and the contrast is ...

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Problems solved by technology

[0002] Among the imaging technologies commonly used in medical imaging diagnosis at present, X-ray transmission imaging, X-ray tomography (CT), and nuclear magnetic resonance imaging all have a large degree of damage to human tissues, and X-ray tomography scanners, nuclear magnetic resonance imaging machines, etc. The cost of B-mode ultrasonic imaging is relatively expensive; B-mode ultrasonic imaging has basically no damage to the human body, and the cost is also low, but because the principle of B-mode ultrasonic imaging is tissue interface reflection imaging, it cannot achieve tomography, and the resolution is low (for simple structures) In vivo tissue, the best resolution is a few millimeters), and the contrast is poor

Optical imaging technology (including time-resolved optical imaging, frequency-domain optical imaging, optical coherence tomography, etc.) has the characteristics of no damage to the human body and high resolution, but because these methods use external light sources, and biological tissues have Strong scattering and absorption, so the current technical level can only achieve imaging of shallow biological tissues with a depth of millimeters, and it is difficult to achieve accurate measurement of deep tissues. At the same time, these optical imaging methods use the optical properties of tissues However, the imaging contrast is only derived from the difference in the optical properties of the tissue, so the imaging contrast is not high

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