Use of aspergillus fumigatus in preparing anti inflammatory immunosuppressant
A technology of Aspergillus fumigatus, immunosuppression, applied in the directions of anti-inflammatory agents, antipyretics, drug combinations, etc., can solve problems such as no reports and the like
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment Construction
[0039] Aspergillus fumigatus (Fumigaclavine C) is obtained from Cynodon dactylon (Cynodon dactylon) Aspergillus sp. endophytic fungi (strain number: CY018) A kind of indole alkaloid isolated from the solid fermentation product of ) (see attached figure 1 ). It is a white needle-like crystal (chloroform / methanol (V / V: 10 / 1)), melting point 192-194°C, IR: v max KBr (cm -1 )3401.5, 3058.2, 2961.7, 1715.7, 1609.4, 1460.9, 1381.0, 1260.8, 749.3; EIMS: 366, 307 (100%), 291, 238, 194, 108, 82, 43; ESIMS: 365 [M-H] - ;ESIMS:367[M+H] + ; 1 H(500MHz) and 13 C (125 MHz) NMR structural analysis is shown in Table 1.
[0040] position
[0041] s: singlet, d: doublet, t: triplet, br: broad
[0042] Fumigaclavine C (Fumigaclavine C) intraperitoneal injection has a significant improvement effect on the liver damage of mice caused by Con A, and its effect includes reducing the increase of transaminase in the serum of Con A model mice (Table 2), improving liver The pathologic...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com