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Preparation method of Chinese medicine capsule for treating ischemic cerebral apoplexy

A technology of ischemic cerebral apoplexy and traditional Chinese medicine capsules, which is applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of low absorption rate of active ingredients, poor therapeutic effect, waste of Chinese herbal medicine resources, etc. problem, achieve the effect of reducing disability rate, reducing cerebrovascular resistance, and reducing recurrence

Inactive Publication Date: 2006-04-12
浙江得恩德制药股份有限公司
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  • Summary
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  • Application Information

AI Technical Summary

Problems solved by technology

Among the existing medicines prepared according to the theory of "promoting blood circulation and removing blood stasis", leeches and horseflies are mostly used as raw medicines in the finished medicines, and the human body has a low absorption rate of their active ingredients, so the therapeutic effect is not very good, and the effective rate is low. At the same time, the amount of medicinal materials required is large, resulting in a waste of traditional Chinese medicinal material resources

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1 Traditional Chinese medicines were weighed: 386.3g of leeches, 193.2g of horseflies, 579.5g of rhubarb, 579.2g of peach kernels and 205.0g of medicinal excipients.

[0017] After immersing the coarse powder of leeches and horseflies with 60% ethanol with a concentration of 2 times of the dosage for 12 hours, add 10 times of the dosage of ethanol to carry out percolation for 48 hours, and the percolation speed is 2.0 ml / min. Concentrate the filtrate under reduced pressure below 50°C until the relative density of the concentrate is 1.25 (40°C), then add 78.2g of silicon dioxide, mix well and dry under vacuum below 50°C to obtain a dry paste; in rhubarb and peach kernels Add water to decoct twice, the weight of water added for the first time is 8 times the total weight of rhubarb and peach kernels, the decoction time is 1.5 hours, the weight of water added for the second time is 5 times the total weight of rhubarb and peach kernels, the decoction time for 1.5 hou...

Embodiment 2

[0019] Weigh Chinese medicine: 420g of leech, 160g of horsefly, 600g of rhubarb, 560g of peach kernel and 265g of medicinal excipients.

[0020] After the coarse powder of leech and horsefly was immersed in 50% ethanol with the concentration of 2 times of the dosage for 12 hours, add 10 times of the dosage of ethanol to carry out percolation for 38 hours, and the percolation speed was 2.5 ml / min. Concentrate the filtrate under reduced pressure below 60°C until the relative density of the concentrate is 1.27 (40°C), then add 78g of silicon dioxide, mix well and dry under vacuum below 60°C to obtain a dry paste; add water to rhubarb and peach kernels Decocting twice, the weight of adding water for the first time is 6 times the total weight of rhubarb and peach kernels, and the decocting time is 2 hours; the weight of adding water for the second time is 5 times the total weight of rhubarb and peach kernels, and the decoction time is 1.5 hours. The resulting decoction is filtered...

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PUM

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Abstract

The Chinese medicine capsule for treating ischemic cerebral apoplexy is prepared with leech, gadfly, rhubarb, peach kernel, and medicinal supplementary material. The preparation process soaking and percolating leech and gadfly, concentration, adding medicinal supplementary material, drying to obtain the first dry ointment; decocting rhubarb and peach kernel, adding ethanol white stirring, letting stand, filtering, concentration, adding medicinal supplementary material and drying to the second dry ointment; mixing the first dry ointment and the second dry ointment, crushing and capsulizing. The separated extraction of animal and plant medicinal materials based on their characteristic raises the treating effect of the medicine, and the medicine has high effective rate in treating apoplexy and other diseases.

Description

technical field [0001] The invention relates to a Chinese patent medicine, in particular to a preparation method of a traditional Chinese medicine capsule for treating ischemic cerebral apoplexy. Background technique [0002] Ischemic stroke is cerebral infarction, which includes cerebral thrombosis, cerebral embolism, etc. Cerebral infarction accounts for 70% to 80% of all strokes, and has increased significantly in recent years, and is developing towards younger age. The main pathological change of cerebral infarction is that on the basis of cerebral arteriosclerosis, thrombus forms in the blood vessels, blocking the blood flow, causing ischemia, hypoxia and necrosis of brain tissue, causing hemiplegia, aphasia, numbness of one side of the body, and walking Instability, incontinence, insanity, dementia, and even vegetative state, partial brainstem infarction and large area cerebral infarction can be fatal. Once suffering from cerebral infarction, it means that the body ha...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61K35/62A61K35/64A61K9/48A61P9/10
Inventor 章国林金春晖胡香红时德远高红玉
Owner 浙江得恩德制药股份有限公司
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