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Left ofloxacin and Pidotimod compound preparation

A technology of levofloxacin and pidotimod, applied in pharmaceutical formulations, medical preparations containing active ingredients, antibacterial drugs, etc., can solve the problem of low level of anti-infection immunity, unrealistic finding of antibiotics, and easy to induce drug resistance and other issues, to achieve the effect of good safety, significant social benefits and moderate price

Inactive Publication Date: 2005-12-21
SUNSTONE TANGSHAN PHARM CO LTD
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

However, in recent years, as the problem of antibiotic resistance has become more and more serious, clinicians still face many problems such as complex, refractory infections and recurrent infections in the process of treating bacterial infectious diseases
At the same time, due to the increasing cycle and cost of developing new antibiotics, it is not realistic to find newer and stronger antibiotics in the short term.
The progress of immunological research shows that such patients generally have the problem of low level of anti-infection immunity, and relying solely on exogenous antibacterial drugs is not enough to completely eliminate pathogenic bacteria, and it is easy to leave hidden dangers of drug resistance. Combination strategies to treat infections, especially the use of appropriate immunotherapeutic drugs, should be the best way to treat bacterial infections by improving the patient's own anti-infection immunity and mobilizing the body's endogenous anti-infection ability

Method used

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  • Left ofloxacin and Pidotimod compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0019] Embodiment sees the following table:

[0020] Table 1 Example

[0021]

[0022] The beneficial effect of the present invention is further illustrated below by the curative effect report.

[0023] Compound preparation of levofloxacin and pidotimod in the treatment of chronic

[0024] Clinical curative effect report on acute exacerbation of bronchitis

[0025] [Objective] To observe the clinical curative effect of compound preparation of levofloxacin and pidotimod on acute exacerbation of chronic bronchitis

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PUM

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Abstract

The invention relates to a compound preparation of levofloxacin and pidotimod for treating bacterial infectious diseases. Its composition is: levofloxacin 200-400mg, pidotimod 800-1600mg. The compound preparation provided by the invention not only directly kills pathogenic bacteria from exogenous aspects through levofloxacin, but also enhances the anti-infection effect through mobilizing endogenous anti-infective immunity through pidotimod, and has obvious synergistic effect.

Description

technical field [0001] The invention relates to a compound preparation of levofloxacin and pidotimod, which is used for treating bacterial infectious diseases. Background technique [0002] Infectious diseases are common problems encountered in clinical work, and about 80% of the infections in adults are caused by bacteria, involving outpatients and inpatients in various clinical departments. The most important clinical method for bacterial infection is the use of various antibiotics, making antibiotic products an important product in the field of pharmaceutical production. However, in recent years, as the problem of antibiotic resistance has become more and more serious, clinicians still face many problems such as complex, refractory infections and recurrent infections in the process of treating bacterial infectious diseases. At the same time, due to the increasing cycle and cost of developing new antibiotics, it is not realistic to find newer and stronger antibiotics in t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/5383A61K38/05A61P31/04
Inventor 韩志强贾晓冬
Owner SUNSTONE TANGSHAN PHARM CO LTD
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