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Cell anti-aging essence and preparation method thereof

An anti-aging and essence technology, applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve the problems of poor absorption and anti-aging effects that need to be improved, to reduce content, improve absorbability, improve The effect of anti-aging activity

Pending Publication Date: 2022-08-05
广州沙艾生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Studies have shown that grape seeds contain anti-aging active ingredients, but the extracts obtained by existing technologies are poorly absorbed by the human body, resulting in the need for improvement in anti-aging effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] As a cellular anti-aging essence according to an embodiment of the present invention, the cellular anti-aging essence includes 2 parts by weight of dandelion extract, 4 parts by weight of licorice root extract, 2 parts by weight of wolfberry leaf extract, 3 parts by weight of Spirulina extract in parts by weight, grape seed extract in 4 parts by weight, cyclobaicaleol in 1 part by weight and 80 parts by weight solvent;

[0030] The solvent of the essence is an ethanol aqueous solution with a volume ratio of 35%;

[0031] The preparation method of the grape seed extract comprises the following steps: (1) degreasing and drying the dried grape seeds to obtain degreasing grape seed powder; (2) decompressing the degreasing grape seed powder in an ethanol alkali solution at 50° C. Reflux extraction for 45 minutes, the material-to-liquid ratio is 1:4, the volume ratio of ethanol in the ethanolic alkali solution is 45%, and the mass concentration of sodium hydroxide in the etha...

Embodiment 2

[0037] As a cellular anti-aging essence according to an embodiment of the present invention, the cellular anti-aging essence includes 2 parts by weight of dandelion extract, 4 parts by weight of licorice root extract, 2 parts by weight of wolfberry leaf extract, 3 parts by weight of Spirulina extract in parts by weight, grape seed extract in 3 parts by weight, cyclobaicalein in parts by weight in 3 parts by weight, and solvent in 80 parts by weight, and the rest are the same as those in Example 1.

Embodiment 3

[0039] As a cellular anti-aging essence according to an embodiment of the present invention, the cellular anti-aging essence includes 2 parts by weight of dandelion extract, 4 parts by weight of licorice root extract, 2 parts by weight of wolfberry leaf extract, 3 parts by weight of Spirulina extract in parts by weight, grape seed extract in 4 parts by weight, cyclobaicaleol in 1 part by weight and 80 parts by weight solvent;

[0040] The solvent of the essence is an ethanol aqueous solution with a volume ratio of 35%;

[0041] The preparation method of the grape seed extract comprises the following steps: (1) pulverizing the dried grape seeds, defatting and drying to obtain a defatted grape seed powder; (2) decompressing the defatted grape seed powder in an ethanol alkali solution at 45° C. Reflux extraction for 45 minutes, the ratio of material to liquid is 1:4, the volume ratio of ethanol in the ethanolic alkali solution is 60%, and the mass concentration of sodium hydroxid...

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PUM

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Abstract

The invention provides cell anti-aging essence and a preparation method thereof. The cell anti-aging essence is prepared from the following components in parts by weight: 1 to 5 parts of dandelion extract, 1 to 5 parts of liquorice overground part extract, 1 to 5 parts of boxthorn leaf extract, 1 to 5 parts of spirulina extract, 1 to 5 parts of grape seed extract, 1 to 5 parts of cyclo-baicaleol and 80 to 100 parts of solvent. The degreased grape seed powder is extracted by using the ethanol alkali solution, so that the absorbability of the grape seed extract is improved, and the anti-aging activity is improved; the anti-aging composition has the advantages that the anti-aging effect is good, the anti-aging effect is good, the plant extract and the cyclo-baicaleol are matched, the content of lipid peroxidation product malondialdehyde (MDA) generated by oxidative stress in a mouse body can be obviously reduced, secretion of TNF-alpha, IL-6 and IL-1beta in rat serum caused by D-Gal is reduced, and the anti-aging performance is synergistically enhanced. The cell anti-aging essence is wide in application range and can be applied to skin care products, and the anti-aging performance is improved.

Description

technical field [0001] The invention relates to the field of cosmetic raw materials, in particular to a cell anti-aging essence and a preparation method thereof. Background technique [0002] Aging is a biological change process, which is caused by the interaction of multiple factors such as genetics and complex internal and external environment. The free radical theory believes that in the process of aging, due to the continuous increase in the level of free radicals, the antioxidant capacity of the body decreases, and external environmental stimuli, mitochondria, and fatty acids can produce various peroxides such as superoxide anion, hydrogen peroxide, and hydroxyl radicals. factor to accelerate the aging process. In the process of oxidative aging in the body, the body has an anti-oxidative aging defense system, and some natural medicines have anti-oxidative aging components. [0003] Studies have shown that grape seeds contain anti-aging active ingredients, but the extr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/9789A61K8/63A61Q19/08
CPCA61K8/99A61K8/9789A61K8/63A61Q19/08A61K2800/5922A61K2800/805
Inventor 徐智峰张新李智耀
Owner 广州沙艾生物科技有限公司
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