Disodium adenosine triphosphate external medicine for preventing and treating myopia as well as preparation method and application of disodium adenosine triphosphate external medicine
A technology of disodium adenosine triphosphate and external medicine, which is applied in the field of medicine, can solve the problems of non-application and side effects of disodium adenosine triphosphate, and achieve the effects of avoiding side effects, dilating peripheral blood vessels, and reducing astigmatism
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Embodiment 1
[0056] Disodium adenosine triphosphate eye drops for preventing and treating myopia, the eye drops are prepared from the following raw materials: 21.05g of adenosine triphosphate disodium, 30.30g of L-methionine, added to 80% water for injection with a total volume of 2000ml, Stir to dissolve completely, then adjust the pH value of the solution to 8.00 by using 30 ml of 4% aqueous sodium hydroxide solution, and add the remaining water for injection to the full amount. The milliosmolarity of the adenosine disodium triphosphate eye drops is 377.65 mosmol / Kg; the concentration of the adenosine disodium triphosphate eye drops in the eye drops is 0.011 g / ml; the pH value of the obtained adenosine triphosphate disodium eye drops is 8.00.
Embodiment 2
[0058] Disodium adenosine triphosphate eye drops for preventing and treating myopia, the eye drops are prepared from the following raw materials: 21.05 g of adenosine disodium triphosphate and 35.35 g of L-methionine, added to 80% water for injection with a total volume of 2000 ml, Stir until completely dissolved, then adjust the pH value of the solution to 9.00 by using 37.50 ml of a 4% aqueous sodium hydroxide solution, and add the remaining water for injection to the full amount. The milliosmolarity of the adenosine disodium triphosphate eye drops is 426.49 mosmol / Kg; the concentration of the adenosine disodium triphosphate eye drops in the eye drops is 0.011 g / ml; the pH value of the obtained adenosine triphosphate disodium eye drops is 9.00.
Embodiment 3
[0060] An external drug of adenosine triphosphate disodium for preventing and treating myopia, the external drug comprising the eye drops described in Embodiment 1-2 and the adenosine triphosphate disodium eye patch;
[0061] Described adenosine triphosphate disodium eye patch includes eye patch and eye patch spunlace non-woven fabric, and described eye patch is prepared from the following raw materials: 21.05g of adenosine triphosphate disodium, 30.30g of L-methionine, 4 % sodium hydroxide solution 30ml, water for injection was added to 3000ml. The milliosmolarity of the adenosine disodium triphosphate eye patch is 251.77 mosmol / Kg;
[0062] The concentration of adenosine disodium triphosphate in the eye patch is 0.007 g / ml; the pH value is adjusted to 7.85 with 30 ml of a 4% aqueous sodium hydroxide solution.
[0063] The eye patch consists of two spunlace non-woven fabrics, both of which are elliptical, with a transverse long axis diameter of 8.1 cm and a longitudinal shor...
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