Silver ion no-clean disinfectant as well as preparation method and application thereof
A technology of disinfectant and silver ions, applied in the field of sanitary cleaning products, can solve the problems of insufficient sterilization ability, inability to kill multiple bacteria and viruses, skin irritation, etc., and achieve good product stability, resistance to drug resistance, and preparation The effect of the simple method
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[0061] Another aspect of the present invention provides a preparation method of a silver ion no-clean disinfectant for preparing the above-mentioned silver ion no-clean disinfectant, the method comprising the following steps:
[0062] Provide each raw material according to the proportion of components;
[0063] The raw materials are mixed uniformly.
[0064] Specifically, the preparation method of silver ion disposable disinfectant comprises the following steps:
[0065] S1. Provide each raw material component.
[0066] S2, dissolve the thickener in deionized water to obtain a thickener solution of 2wt% to 5wt%, add the pH regulator according to the mass ratio of thickener:pH regulator=(1~2):1, and mix evenly , wrap the beaker with tin foil, and place it in a cool place at room temperature to swell for 10h to 12h.
[0067] S3. Mix ethanol, silver nitrate, Coptis chinensis extract, stabilizer and humectant to obtain a premixed solution, add it to the swollen thickener soluti...
Embodiment 1
[0081] 1. Preparation of Coptis chinensis extract
[0082] The rhizomes of Coptidis chinensis are air-dried, chopped into pieces of 1 cm to 2 cm and crushed to obtain Coptis chinensis pretreatment powder. Weigh 10 g of Coptis chinensis pretreatment powder and mix it with 100 mL of 95% ethanol, wrap the mouth of the beaker with silver foil, put it in an ultrasonic machine, and ultrasonicate for 3 hours. Solid Coptis chinensis and dregs are obtained to obtain an extract after extraction, and the solvent is removed to about 12mL by distillation to obtain Coptis chinensis extract, and finally the berberine content is measured by high performance liquid chromatography to be 25mg / mL.
[0083] 2. Preparation of Carbomer Gel
[0084] Weigh 1 g of carbomer, dissolve it in 50 mL of deionized water to obtain a 2% carbomer solution, add 0.5 g of triethanolamine, mix well, wrap the beaker with tin foil, and swell in a cool place at room temperature for 12 hours.
[0085] 3. Preparation o...
Embodiment 2
[0096] 1. Preparation of Coptis chinensis extract
[0097] The rhizomes of Coptidis chinensis are air-dried, chopped into 1cm-2cm pieces and crushed to obtain Coptis chinensis pretreatment powder. Weigh 10 g of Coptis chinensis pretreatment powder and mix it with 100 mL of 95% ethanol, wrap the mouth of the beaker with silver foil, put it into the ultrasonic tank, and ultrasonicate for 2 hours, 30 minutes each time, divided into four times. The suction filtration device performs suction filtration on the solvent to remove the solid coptis and dregs to obtain the extracted extract, and the solvent is removed to about 8 mL by distillation to obtain the coptis extract, and finally the berberine content is measured by high performance liquid chromatography. is 50 mg / mL.
[0098] 2. Carbomer gel preparation process:
[0099] Weigh 1 g of carbomer, dissolve it in 50 mL of deionized water to obtain a 2% carbomer solution, add 0.5 g of triethanolamine, mix well, wrap the beaker with...
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