Bioreactor constant temperature system

Abstract

The invention provides a bioreactor constant temperature system which is characterized in that the bioreactor constant temperature system comprises a first constant temperature device; the first constant temperature device comprises a base, a sleeve and a first constant temperature adjusting module; the sleeve is installed on the base, and the inner side of the sleeve and the base jointly form an accommodating space which is provided with an opening in the upper part and can be used for placing a bioreactor; the first constant temperature adjusting module comprises at least one Peltier tile which is mounted along the side wall of the sleeve; and the first constant temperature adjusting module is used for adjusting the temperature of the bioreactor placed in the accommodating space and enabling the bioreactor to be in a constant-temperature state. The Peltier tile is used for providing heat radiation to heat the bioreactor, the thermal inertia of the Peltier tile is very small, and the cooling and heating time is short. By adopting the Peltier tile, the bioreactor constant temperature system has the characteristics of capability of continuously working, no pollution, no rotation effect, small vibration during working, low noise, long service life, easiness in installation and the like.

Description

technical field [0001] The invention relates to the technical field of cell culture, in particular to a constant temperature system for a bioreactor. Background technique [0002] In vitro cell therapy requires the use of bioreactors to carry cells for in vitro treatment, and cells must have a suitable temperature for vigorous growth and corresponding functions in the bioreactor. In recent years, with the continuous development of basic theories, technical means and clinical medical exploration research such as stem cell therapy, immune cell therapy and gene editing, cell therapy products have provided new treatment ideas and methods for some serious and refractory diseases; cells In vitro treatment first requires culturing the cells to keep the cells in a relatively stable state, maintaining the vigorous growth of the cultured cells and maintaining their functions, and must have a constant and appropriate temperature. Different types of cells have different requirements fo...

AI Technical Summary

Problems solved by technology

[0004] Whether it is a water-proof constant temperature incubator or an electric constant temperature incubator, an insulation layer is generally installed. In addition, the heating device is relatively large, so the overall volume is relatively large, which also leads to an increase in the heating range and low heating efficiency.

Since the heating part heats the box and other parts at the same time, it is also necessary to install a heat dissipation device, which will bring a lot of noise, while the electric heating constant temperature incubator uses a blower to dissipate heat, which makes the noise even louder

Moreover, although the bioreactor can be placed in an incubator to maintain a constant temperature, when the treatment is performed, the bioreactor needs to exchange liquid, and the existing constant temperature incubator needs more heating power to keep the bioreactor at a constant temperature. Therefore, the existing constant temperature culture The box cannot meet the constant temperature requirements of the bioreactor

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