Ultra-violet absorbing compounds

Abstract

The present application relates to novel compounds able to absorb UV radiation and comprise antimicrobial properties as well. The compounds herein described are novel and undisclosed scytonemin analogs, able to absorb up to 90% of UV-A radiation and can cover a broader UV to blue light absorption range from 293 nm to 500 nm. When mixtures of more than one compound are used, their synergetic absorption properties can cover an even broader spectrum within 293 nm to 500 nm. The compounds described present faint coloration, and some are even colorless, therefor the present compounds can be easily incorporated in formulations to be used in cosmetic products, sunscreens or lenses for sunglasses.

Description

technical field [0001] The present application relates to novel ultraviolet absorbing compounds. Background technique [0002] Ultraviolet (UV) radiation, the most harmful and mutagenic component of the solar spectrum, is a major cause of premature skin aging, eye damage, and some forms of skin cancer [1]. In fact, 50-90% of the total number of reported skin cancers may be caused by UV [2]. In 2018, almost 300.000 new cases were reported worldwide [3]. Although the effects of UV-B (280-320nm), especially carcinogenicity, have been known for many years, the harmful effects of UV-A (320-400nm) have generally been ignored. In fact, UV-A radiation accounts for 95% of all UV light reaching the earth's surface, and it can penetrate deep into the skin and eyes, affecting connective tissue and blood vessels. This ability leads to eye damage, loss of skin elasticity, wrinkles, and thus premature aging [4]. In addition, recent studies have shown that UV-A can also stimulate the de...

AI Technical Summary

Problems solved by technology

Substitutions in the scyneman backbone lead to a change in the absorption profile, rendering these molecules colorless or faintly colored was unexpected and has not been observed before

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