Medical composite self-pumping dressing with multi-layer structure as well as preparation method and application of medical composite self-pumping dressing

A multi-layer structure, self-pumping technology, used in dressings, pharmaceutical formulations, non-adhesive dressings, etc., can solve the problems of complicated healing process, achieve good application prospects, improve liquid absorption capacity, and reduce manufacturing costs.

Inactive Publication Date: 2022-01-07
XI'AN POLYTECHNIC UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The remaining biological fluids constantly moisturise the wound, complicating the healing process

Method used

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  • Medical composite self-pumping dressing with multi-layer structure as well as preparation method and application of medical composite self-pumping dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A method for preparing a multilayered medical composite self-pump dressing, comprising the following steps:

[0040] Step 1: Dissolve 2g of sodium alginate in 100ml of distilled water to prepare a 2% sodium alginate aqueous solution;

[0041] Step 2: Stir magnetically for 3 hours to form a homogeneous solution;

[0042] Step 3: Stand still for 24 hours under the conditions of relative humidity of 60% and temperature of 25°C;

[0043] Step 4: Use the double-needle bed Raschel warp knitting machine to knit the warp-knitted three-dimensional spacer fabric whose surface layer is knitting chain + weft insertion; the three-dimensional spacer fabric adopts double-needle bed Raschel warp knitting with a total of 6 bars from GB1 to GB6 Machine weaving, the yarns on GB2 and GB5 are hydrophobic fiber multifilaments, the yarns on GB1 and GB6 are carbon fiber tows, and the yarns on GB3 and GB4 are hydrophobic fiber monofilaments with a diameter of 0.2mm; GB1 and GB2 Knit the top l...

Embodiment 2

[0050] A method for preparing a multilayered medical composite self-pump dressing, comprising the following steps:

[0051] Step 1: Dissolve 5g of sodium alginate in distilled water to prepare an aqueous solution of sodium alginate with a mass fraction of 5%;

[0052] Step 2: Stir magnetically for 6 hours to form a homogeneous solution;

[0053] Step 3: Stand still for 20 hours under the conditions of relative humidity of 65% and temperature of 28°C;

[0054] Step 4: Use the double-needle bed Raschel warp knitting machine to knit the warp-knitted three-dimensional spacer fabric whose surface layer is knitting chain + weft insertion; the three-dimensional spacer fabric adopts double-needle bed Raschel warp knitting with a total of 6 bars from GB1 to GB6 Machine weaving, the yarns on GB2 and GB5 are hydrophobic fiber multifilaments, the yarns on GB1 and GB6 are carbon fiber tows, and the ones on GB3 and GB4 are hydrophobic fiber monofilaments; The front needle bed weaves the t...

Embodiment 3

[0061] A method for preparing a multilayered medical composite self-pump dressing, comprising the following steps:

[0062] Step 1: Dissolve 10 g of sodium alginate in distilled water to prepare an aqueous solution of sodium alginate with a mass fraction of 10%;

[0063] Step 2: Stir magnetically for 5 hours to form a homogeneous solution;

[0064] Step 3: Stand still for 20 hours under the conditions of relative humidity of 65% and temperature of 22°C;

[0065] Step 4: Use the double-needle bed Raschel warp knitting machine to knit the warp-knitted three-dimensional spacer fabric whose surface layer is knitting chain + weft insertion; the three-dimensional spacer fabric adopts double-needle bed Raschel warp knitting with a total of 6 bars from GB1 to GB6 Machine weaving, the yarns on GB2 and GB5 are hydrophobic fiber multifilaments, the yarns on GB1 and GB6 are carbon fiber tows, and the yarns on GB3 and GB4 are hydrophobic fiber monofilaments with a diameter of 0.2mm; GB1 a...

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Abstract

The invention discloses a medical composite self-pumping dressing with a multilayer structure as well as a preparation method and application thereof, and relates to the technical field of functional materials. The composite self-pumping dressing comprises a three-dimensional spacer fabric, a nanofiber membrane arranged on a top surface layer of the three-dimensional spacer fabric and an aerogel layer filled in the three-dimensional spacer fabric, the three-dimensional spacer fabric is a hydrophilic three-dimensional spacer fabric; and the aerogel layer is a hydrophilic aerogel layer. The dressing provided by the invention is reasonable in structural design and simple in manufacturing process, the capability of absorbing redundant exudate of the medical dressing is improved, active substances are released to promote growth of wound tissues, a wound can be kept moist, proper buffer performance is provided, and healing of the wound is promoted.

Description

technical field [0001] The invention relates to the technical field of functional materials, in particular to a medical composite self-pump dressing with a multi-layer structure and its preparation method and application. Background technique [0002] Periwound management of biological fluids is a prerequisite for wound healing, including control of bleeding and removal of excess biological fluids. Excessive biological fluids, which tend to overhydrate wounds, are an overlooked but widespread problem that impedes the wound healing process. Conventional hydrophilic dressings usually absorb part of the biological fluids, but due to their own hydrophilicity, biological fluids will inevitably remain at the interface between the wound and the dressing. The remaining biological fluids constantly moisturise the wound, complicating the healing process. Contents of the invention [0003] The purpose of the present invention is to solve the deficiencies in the above-mentioned back...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/00A61L15/28A61L15/42A61L15/44D04B1/14D01D5/00
CPCA61F13/00017A61F13/00029A61F13/00987A61L15/28A61L15/42A61L15/44D04B1/14D01D5/0084D01D5/003A61L2300/412A61L2400/12C08L5/04
Inventor 支超朱海余灵婕王亚妮孟家光薛涛王永臻刘亚明程燕婷
Owner XI'AN POLYTECHNIC UNIVERSITY
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