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Pharmaceutical composition for treating xerostomia after nasopharyngeal carcinoma radiotherapy

A technology for radiotherapy and xerostomia of nasopharyngeal carcinoma, which is applied in drug combinations, antineoplastic drugs, and pharmaceutical formulations, and can solve problems such as ineffective curative effects

Inactive Publication Date: 2021-12-28
柳州市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many reports use nourishing yin and promoting body fluid as the treatment principle. Although some effects have been obtained, the curative effect is not significant

Method used

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  • Pharmaceutical composition for treating xerostomia after nasopharyngeal carcinoma radiotherapy
  • Pharmaceutical composition for treating xerostomia after nasopharyngeal carcinoma radiotherapy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1——a pharmaceutical composition for treating xerostomia after radiotherapy for nasopharyngeal carcinoma

[0042] Its preparation raw materials include: Guizhi 6g, Paojiang 10g, Rehmannia glutinosa 30g, Ophiopogon japonicus 20g, Nansha ginseng 30g, Tianhuafen 30g, Polygonatum 15g, Lily 30g, Dendrobium 15g, Lycium barbarum 20g, Ume 20g, Paeoniae Alba 20g 10g of licorice;

[0043] The preparation steps include: putting all the raw materials into a decocting pot, pouring water to cover the raw materials by about 2 cm to 3 cm, soaking for about half an hour; Take it twice in the morning and evening.

Embodiment 2

[0044] Embodiment 2—the pharmaceutical composition for the treatment of xerostomia after radiotherapy for nasopharyngeal carcinoma

[0045] Its preparation raw materials include: Guizhi 6g, Paojiang 6g, Rehmannia glutinosa 20g, Ophiopogon japonicus 12g, Nansha ginseng 18g, Tianhuafen 30g, Polygonatum odoratum 12g, Lily 30g, Dendrobium 60g, Lycium barbarum 12g, Black plum 20g, Radix paeoniae Alba 30g, Licorice 6g;

[0046] The preparation steps include: putting all the raw materials into a decocting pot, pouring water to cover the raw materials by about 2 cm to 3 cm, soaking for about half an hour; Take it twice in the morning and evening.

Embodiment 3

[0047] Embodiment 3 - the pharmaceutical composition for the treatment of xerostomia after radiotherapy for nasopharyngeal carcinoma

[0048] Its preparation raw materials include: Guizhi 9g, Paojiang 15g, Rehmannia glutinosa 20g, Ophiopogon japonicus 15g, Nansha ginseng 20g, Tianhuafen 20g, Polygonatum odoratum 10g, Lily 20g, Dendrobium 20g, Lycium barbarum 9g, Black plum 15g, Paeoniae Alba 30g, Licorice 6g;

[0049] The preparation steps include: putting all the raw materials into a decocting pot, pouring water to cover the raw materials by about 2 cm to 3 cm, soaking for about half an hour; Take it twice in the morning and evening.

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Abstract

The invention discloses a pharmaceutical composition for treating xerostomia after nasopharyngeal carcinoma radiotherapy, and relates to the technical field of traditional Chinese medicines. The pharmaceutical composition is prepared from the following raw materials: cassia twig, baked ginger, radix rehmanniae recen, radix ophiopogonis, radix adenophorae, radix trichosanthis, radix polygonati officinalis, lily, herba dendrobii, fructus lycii, fructus mume, radix paeoniae alba and liquorice root; and furthermore, the pharmaceutical composition is prepared from the following components in parts by weight: 3-9 parts of the cassia twig, 3-15 parts of the baked ginger, 10-30 parts of the radix rehmanniae recen, 6-20 parts of the radix ophiopogonis, 9-30 parts of radix adenophorae, 15-30 parts of the radix trichosanthis, 6-15 parts of the radix polygonati officinalis, 15-30 parts of the lily, 15-30 parts of the herba dendrobii, 6-20 parts of the fructus lycii, 10-20 parts of the fructus mume, 15-30 parts of the radix paeoniae alba and 3-10 parts of the liquorice root. The pharmaceutical composition has the effects of seeking yin from yang and helping produce saliva and slake thirst, and has a remarkable effect on treating xerostomia after nasopharyngeal carcinoma radiotherapy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating xerostomia after radiotherapy of nasopharyngeal carcinoma. Background technique [0002] Nasopharyngeal carcinoma belongs to the category of "dishonor" and "ear, nose and throat cancer" in the motherland's medicine. Radiation therapy is the treatment of choice. Salivary glands are highly sensitive to radiation, and the radiation loss of salivary glands during radiotherapy is the root cause of xerostomia after radiotherapy. Traditional Chinese medicine believes that radiation is a poisonous evil with a "hot" nature. "Heat is yang evil, which can easily cause sores and carbuncles." Skin redness, burning pain; "heat evil easily consumes qi and injures body fluid", so most patients also show thirst and preference to drink, dry throat and mouth, fatigue and lack of energy, short red urine, constipation, red tongue with little moss and thr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P11/02A61P11/04A61P35/00A61P1/02
CPCA61K36/54A61K36/9068A61K36/804A61K36/8968A61K36/342A61K36/428A61K36/8969A61K36/8967A61K36/8984A61K36/815A61K36/736A61K36/71A61K36/65A61K36/484A61P35/00A61P11/02A61P11/04A61P1/02A61K2300/00
Inventor 郭会游兴信石彧王志祥曾湘宜韦敏梅冯驭臣郑燕怡潘志格于鹏梁艳艳
Owner 柳州市中医医院
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