Traditional Chinese medicine probiotic fermentation extract for improving oral cavity problems and preparation method and application thereof

A technology of probiotics and extracts, which is applied in the field of fermented extracts of traditional Chinese medicine probiotics and its preparation for improving oral problems. Effects of improvement, reduction of bitterness and astringency, and increase of potency

Active Publication Date: 2021-12-21
GUANGDONG YIKEWEI BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there is basically no functional mouthwash or other oral products containing traditional Chinese medicine on the market, especially mouthwash or other oral products that can solve problems such as bad breath, swelling and pain on the gums, oral ulcers, etc.
Mouthwashes on the market are generally ordinary mouthwashes or other oral products, or mouthwashes or other oral products with western medicine anti-bacterial agents, and some claim to add traditional Chinese medicine (honeysuckle, skullcap, wild chrysanthemum, tea extract, etc.) Mouthwash or other oral products, but these traditional Chinese medicines are only conceptual additions and cannot play a very good role
Traditional Chinese medicine has good efficacy, but there are few mouthwashes on the market that can really play the role of traditional Chinese medicine (non-conceptual addition)
In addition, traditional Chinese medicine is generally bitter, and the color is generally brown to black. Some people will mind the smell and taste of traditional Chinese medicine, which is difficult to accept.

Method used

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  • Traditional Chinese medicine probiotic fermentation extract for improving oral cavity problems and preparation method and application thereof
  • Traditional Chinese medicine probiotic fermentation extract for improving oral cavity problems and preparation method and application thereof
  • Traditional Chinese medicine probiotic fermentation extract for improving oral cavity problems and preparation method and application thereof

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preparation example Construction

[0053] A preparation method of a traditional Chinese medicine probiotic fermented extract for improving oral problems, comprising the following steps:

[0054] Traditional Chinese medicine extraction step: crush the Chinese medicinal materials in the traditional Chinese medicine prescription, add water to extract, and then add xylitol, erythritol and sucrose;

[0055] Sterilization step: adjust the pH value to 6.0-6.5, sterilize, transfer the sterilized solution to a cleaned and sterilized fermenter, and set aside;

[0056] The step of cultivating the probiotic seed liquid: inserting Lactobacillus salivarius and Lactobacillus paracasei into the corresponding medium respectively, after culturing, transferring them to the liquid medium respectively, and culturing again to obtain the probiotic seed liquid;

[0057] Fermentation step: add the probiotic seed liquid and yeast powder into the fermenter, and ferment. After the fermentation is completed, the traditional Chinese medicin...

Embodiment 1

[0074]A traditional Chinese medicine probiotic fermented extract capable of improving oral problems (yin deficiency type), prepared from the following raw materials: 12 parts of traditional Chinese medicine prescription, 1.0 part of xylitol, 0.5 part of erythritol, and 2.4 parts of sucrose.

[0075] The preparation method of the above-mentioned traditional Chinese medicine probiotic fermentation extract comprises the following steps:

[0076] (1) Chinese herbal medicines are crushed and passed through a 16-mesh sieve to obtain a coarse powder. Add 8 times the amount of water and heat and reflux for extraction for 1.5 hours. After the extraction is completed, filter and the filtrate is set aside. Extract for 1.5 hours, combine with the first extract, add xylitol, erythritol, sucrose, etc., adjust the pH to 6.0-6.5, and boil for 30 minutes to sterilize.

[0077] (2) Transfer the inactivation solution to a cleaned and sterilized fermenter for later use.

[0078] (3) Prepare stra...

Embodiment 2

[0090] A traditional Chinese medicine probiotic fermented extract capable of improving oral problems (yin-deficiency type), prepared from the following raw materials: 8 parts of traditional Chinese medicine prescriptions, 0.8 parts of xylitol, 0.5 parts of erythritol, and 2.0 parts of sucrose.

[0091] The preparation method of the above-mentioned traditional Chinese medicine probiotic fermentation extract comprises the following steps:

[0092] (1) Chinese herbal medicines are crushed and passed through a 24-mesh sieve to obtain a coarse powder. Add 10 times the amount of water and extract by ultrasonic for 40 minutes. Extraction conditions: temperature 35°C, ultrasonic power: 1200 watts / single ultrasonic head, ultrasonic for 2 seconds and stop for 1 second . After the extraction is completed, add xylitol, erythritol, sucrose, etc., adjust the pH value to 6.0-6.5, and boil for 30 minutes to sterilize.

[0093] (2) Transfer the inactivation solution to a cleaned and sterilize...

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Abstract

The invention discloses a traditional Chinese medicine probiotic fermentation extract for improving oral cavity problems and a preparation method thereof. The traditional Chinese medicine probiotic fermentation extract is prepared by fermenting a traditional Chinese medicine extracting solution obtained by extracting a traditional Chinese medicine formula with saccharomycetes and lactobacillus; before fermentation and / or after fermentation is completed, a flavor regulator is added; and the traditional Chinese medicine formula comprises the following components in equal parts by weight: radix rehmanniae recen, prepared rehmannia root, radix asparagi, radix ophiopogonis, folium eriobotryae, radix scutellariae, dendrobe, fructus aurantii, honey-fried licorice root, oriental wormwood and agastache rugosus. The traditional Chinese medicine probiotic fermentation extract is converted by probiotics in advance, so that the content of effective components can be increased, or part of other components can be converted into effective components, and the defects that the traditional Chinese medicine is not converted in advance, the action time of an oral product in the oral cavity is short and the action is limited are overcome. Meanwhile, the problems of insufficient taste, smell and color and the like when the traditional Chinese medicine extract is applied to oral hygiene products can be solved. The traditional Chinese medicine probiotic fermentation extract provided by the invention can be applied to oral hygiene products and oral health products.

Description

technical field [0001] The invention relates to the technical field of application of probiotics, in particular to a traditional Chinese medicine probiotic fermented extract for improving oral problems, a preparation method and application thereof. Background technique [0002] In recent years, due to the continuous improvement of living standards, people's awareness of hygiene has also been continuously improved, and the proportion of people who use oral hygiene products such as mouthwash is also on the rise. At the same time, bad living habits, especially staying up late, exercising less, working long hours, stressful, and eating cold drinks, will affect the liver, spleen and stomach, and damage liver yin and spleen yin. These bad living habits can also lead to impaired human immunity, and more and more problems such as swollen gums and oral ulcers. In this regard, most people will buy Niuhuang Shangqing tablets and cediodine buccal tablets for treatment; some people will...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K9/68A61K47/26A61K8/9789A61K8/9794A61K8/34A61Q11/00A61P1/02A61P29/00C12P1/02C12P1/04C12R1/645C12R1/225
CPCA61K36/804A61K36/8965A61K36/8968A61K36/73A61K36/539A61K36/8984A61K36/752A61K36/484A61K36/282A61K36/532A61K9/0058A61K9/006A61K47/26A61K8/9789A61K8/9794A61K8/345A61Q11/00A61P1/02A61P29/00C12P1/02C12P1/04
Inventor 花铁果张文朋金庭飞
Owner GUANGDONG YIKEWEI BIOLOGICAL TECH CO LTD
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