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Tooth gel with remineralization capability, tooth paste and preparation method of tooth gel

A technology of remineralization ability and tooth gel, applied in the fields of oral health and bionic biomaterial engineering, can solve the problems of failure to meet user needs, collapse of the gel skeleton structure, damage to the mechanical hardness of the enamel surface, etc. Ease of use, improved remineralization ability, improved effect of treatment

Active Publication Date: 2021-12-07
CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional tooth whitening strips have the following problems: ①Hydrogen peroxide will oxidize the adhesive in the product formula, resulting in the collapse of the gel skeleton structure and poor stability of the product over time; ②The gel layer of the tooth strip has poor water resistance, resulting in Hydrogen peroxide has a short action time on teeth, and the whitening effect is not obvious, which cannot meet the needs of users; ③Hydrogen peroxide will bring many side effects to teeth and oral cavity, such as damage to the mechanical hardness of the enamel surface, soft tissue irritation, tooth sensitivity, acute pulpitis
[0009] The advantages of remineralization mechanism can make up for the shortcomings of traditional whitening strips and cold light whitening technology. At the same time, the remineralization solution used in remineralization treatment has a certain remineralization ability, but it is inconvenient to use, and the remineralization effect needs to be improved

Method used

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  • Tooth gel with remineralization capability, tooth paste and preparation method of tooth gel
  • Tooth gel with remineralization capability, tooth paste and preparation method of tooth gel
  • Tooth gel with remineralization capability, tooth paste and preparation method of tooth gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] A tooth whitening strip with remineralization ability, made of three-layer structure: release liner, gutta-percha layer and peeling backing layer, wherein the anti-adhesive liner and one side of the gutta-percha layer are closely adhered, and the side of the gutta-percha layer The thickness is 100um, active ingredients are dispersed in the gutta-percha layer, and the other side of the gutta-percha layer is closely adhered to the peeled backing layer;

[0049] The release liner is a transparent soft film sticky adhesive layer selected from natural polymers;

[0050] The described release backing layer is a transparent film selected from the material sheet of PET material;

[0051] The gutta-percha layer is a water-insoluble film layer made of the following components by mass ratio:

[0052] Active ingredient 35%,

[0053] Thickener 20%,

[0054] Solvent 25%,

[0055] Solid dispersant 19%,

[0056] Flavor 0.2%,

[0057] Sweetener 0.3%,

[0058] pH regulator 0.5%; ...

Embodiment 2

[0083] A tooth whitening strip with remineralization ability, made of three-layer structure: release liner, gutta-percha layer and peeling backing layer, wherein the anti-adhesive liner and one side of the gutta-percha layer are closely adhered, and the side of the gutta-percha layer The thickness is 300um, active ingredients are dispersed in the gutta-percha layer, and the other side of the gutta-percha layer is tightly adhered to the peeled backing layer;

[0084] The release liner is an opaque soft film sticky adhesive layer selected from fabrics;

[0085] The peeling backing layer is a transparent film selected from foils of PET materials;

[0086] The gutta-percha layer is a water-insoluble film layer made of the following components by mass ratio:

[0087] Active ingredients 20%,

[0088] Thickener 41%,

[0089] Solvent 20%,

[0090] Solid dispersant 17.8%,

[0091] Flavor 0.1%,

[0092] Sweetener 1.0%,

[0093] pH regulator 0.1%;

[0094] The active ingredients ...

Embodiment 3

[0115] A toothpaste with remineralization ability, made of three-layer structure: release liner, gutta-percha layer and release backing layer, wherein the anti-adhesive liner and one side of the gutta-percha layer are closely adhered, the thickness of the gutta-percha layer 200um, effective ingredients are dispersed in the gutta-percha layer, and the other side of the gutta-percha layer is closely adhered to the peeled backing layer;

[0116] The release liner is a transparent soft film sticky adhesive layer selected from films;

[0117] The peeling backing layer is an opaque film selected from paper made of PET material;

[0118] The gutta-percha layer is a water-insoluble film layer made of the following components by mass ratio:

[0119] Active ingredient 3.1%,

[0120] Thickener 20%,

[0121] Solvent 70%,

[0122] Solid dispersant 5%,

[0123] Fragrance 0.6%,

[0124] Sweetener 1.0%,

[0125] pH regulator 0.3%;

[0126] The active ingredient is made of bioactive in...

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Abstract

The invention discloses a tooth gel with remineralization ability, a tooth paste and a preparation method of the tooth gel. The tooth gel comprises the following raw material components in percentage by mass: 1-35% of effective components, 20-60% of a thickening agent, 20-70% of a solvent, 5-25% of a solid dispersing agent, 0.1-0.8% of essence, 0.1-1.0% of a sweetening agent and 0.1-1.0% of a pH regulator; preparation raw materials of the effective components comprise calcium phosphate and / or bioactive glass; and the tooth paste comprises a three-layer structure, namely an anti-sticking lining, a gutta-percha layer and a stripping backing layer, the anti-sticking lining is adhered to one side of the gutta-percha layer, the other side of the gutta-percha layer is adhered to the stripping backing layer, and the gutta-percha layer is tooth gel. The product provided by the invention is convenient to carry and use, has the effects of desensitization, remineralization, antibiosis, caries prevention, whitening and the like, has important effects and meanings on prevention and treatment of oral diseases, and has small or no irritation to oral soft tissues.

Description

technical field [0001] The invention belongs to the technical field of oral health and bionic biomaterial engineering technology (biomineralization), and in particular relates to a tooth jelly with remineralization ability, a tooth paste and a preparation method of the tooth jelly. Background technique [0002] Oral health is an important part of general health. However, caries, periodontal disease and dentin sensitivity are still the most common oral diseases in the world, seriously affecting people's quality of life. The prevalence of these oral diseases develops gradually over time, and the remineralization of dental tissues is expected to block the development of diseases and repair damaged teeth. [0003] In addition, with the improvement of people's living standards, people's awareness of oral aesthetics is becoming stronger and stronger, and they are paying more and more attention to dental beauty. Teeth whitening is one of the more popular tooth cosmetic methods at ...

Claims

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Application Information

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IPC IPC(8): A61K8/24A61K8/21A61K8/25A61K8/19A61K8/20A61K8/02A61Q11/00A61P1/02
CPCA61K8/24A61K8/21A61K8/25A61K8/19A61K8/20A61K8/0208A61Q11/00A61P1/02A61K8/0237A61K8/042A61K2800/48A61K2800/805C03C4/0021
Inventor 陈晓婧李莉莎刘欧胜周君男陈楚潇
Owner CENT SOUTH UNIV
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