Preparation method of absorbable medical suture coated with collagen

Abstract

The invention relates to a preparation method of an absorbable medical suture coated with collagen. The preparation method comprises the following steps: (1) collagen fibers separating; (2) purification; (3) rinsing; (4) cutting; (5) virus inactivation twice; (6) chrome tanning; (7) washing; (8) crosslinking; (9) dehydrating; (10) coating; and (11) polishing. The suture body is soft, easy to operate, good in positioning performance and high in tensile strength and knotting strength; medical and edible additives and vitamins are added, so that the harm of chemical residues to a human body is avoided, the biocompatibility is good, and the inflammatory response in wound healing is reduced; moreover, the needle and thread connection is smooth, the operation resistance is small, the dragging is slight, and the damage is extremely small.

Description

technical field [0001] The invention belongs to the technical field of medical equipment, and relates to a preparation method of medical sutures, in particular to a preparation method of collagen-coated absorbable medical sutures. Background technique [0002] At present, the absorbable medical suture widely used in clinical practice is a new type of suture material that can be degraded and absorbed by the human body after being implanted in human tissue during surgical suturing, and it does not need to be removed. Its quality is directly related to the recovery of postoperative patients, and it marks the manufacturing technology level of products in the field of contemporary medical devices. [0003] The imported absorbable chemically synthesized suture (PGA) used in current clinical operations is a multi-strand braided structure, which has certain defects: foreign objects and dead bacteria are easy to hide in the gaps of the thread structure, and the surface is rough, whic...

AI Technical Summary

Problems solved by technology

[0003] The imported absorbable chemically synthesized suture (PGA) used in current clinical operations is a multi-strand braided structure, which has certain defects: foreign objects and dead bacteria are easy to hide in the gaps of the thread structure, and the surface is rough, which greatly damages human tissues.

At the same time, the chemical substances and ethylene oxide residues in the line body have potential side effects that affect the recovery of patients; the chemical synthesis line has a short shelf life, strict storage environment requirements, and high storage risk

[0004] Since the 1980s, bioabsorbable sutures have been widely used clinically. The threads are hard, knotted unstable, and knots are easy to slide. Inflammation is easy to occur during the period, which directly affects the quality of the operation and increases the pain of the patient

However, ordinary suture needles are connected by punching presses and slotted thread covering needles. The tails of the needles are prone to produce irregular shapes such as flat mouths, ellipses, and ribs.