Magnetic particle imaging reconstruction method from time-frequency domain signal to two-dimensional image

Abstract

The invention belongs to the field of image reconstruction, particularly relates to a magnetic particle imaging reconstruction method, system and equipment from a time-frequency domain signal to a two-dimensional image, and aims to solve the problems of low reconstruction quality and efficiency caused by the fact that an original one-dimensional time domain or frequency domain signal of magnetic particle imaging is used for reconstruction in an existing magnetic particle imaging reconstruction method. The method comprises the following steps: acquiring an MPI image to be reconstructed; after acquisition, extracting a one-dimensional time domain signal of the MPI image to be reconstructed as an input signal; converting an input signal into a two-dimensional time-frequency domain signal through Fourier transform, and preprocessing the two-dimensional time-frequency domain signal; and inputting the preprocessed two-dimensional time-frequency domain signal into the trained neural network model to obtain a reconstructed MPI image. According to the invention, the quality and efficiency of MPI image reconstruction in the prior art are improved.

Description

technical field [0001] The invention belongs to the field of image reconstruction, and in particular relates to a magnetic particle imaging reconstruction method, system and equipment from time-frequency domain signals to two-dimensional images. Background technique [0002] Existing medical imaging technologies such as CT, MRI, SPECT and other methods all have problems such as high harm, poor positioning, and low precision. In recent years, a new tracer-based imaging method—magnetic particle imaging (MPI) has been proposed. Using tomographic imaging technology, MPI can accurately locate tumors or targets by detecting the spatial concentration distribution of superparamagnetic iron oxide nanoparticles (SPIOs) that are harmless to the human body. It has three-dimensional imaging, high temporal and spatial resolution and high sensitivity. features. In addition, MPI does not display anatomical structures and has no background signal interference, so the intensity of the signa...

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Problems solved by technology

[0004] In order to solve the above-mentioned problems in the prior art, that is, in order to solve the problem that the existing magnetic particle imaging reconstruction method uses the original one-dimensional time domain or frequency domain signal of magnetic particle imaging for reconstruction, resulting in low reconstruction quality and efficiency, the present invention In the first aspect, a magnetic particle imaging reconstruction method from a time-frequency domain signal to a two-dimensional image is proposed, which includes the following steps:

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