Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Chicken feather oligopeptide as well as extraction method and application thereof

An extraction method and oligopeptide technology, applied in the field of chicken feather oligopeptides and its extraction, to achieve the effects of improving hair loss, promoting hair growth, and promoting proliferation

Pending Publication Date: 2021-11-05
广东完美生命健康科技研究院有限公司 +2
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In view of the relatively stable chemical structure of keratin, there are certain limitations in the extraction and separation of keratin in the past

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chicken feather oligopeptide as well as extraction method and application thereof
  • Chicken feather oligopeptide as well as extraction method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0022] [NEBM]BF used in the present invention 4 The preparation method is as follows:

[0023] Add 23.0g of N-ethylmorpholine into 20mL of acetone, heat and stir at 70°C, and slowly add 27.4g of n-bromobutane to react, continue to stir and reflux for 36h, vacuum-dry for 12h after vacuum distillation, acetone recrystallization, Obtain light yellow crystals; take 25.2 g of the above light yellow crystals and add them to 125 mL of acetonitrile, then add 10.5 g of ammonium fluoroborate, stir and react for 48 hours, then filter, add anhydrous magnesium sulfate to the filtrate, filter out the magnesium sulfate, evaporate under reduced pressure After removing the solvent, dry it under vacuum at 50°C for 12 hours, and the obtained white solid is [NEBM]BF 4 ionic liquid.

Embodiment 1

[0025] A kind of embodiment of the extraction method of chicken feather oligopeptide of the present invention, the extraction method described in the present embodiment comprises the following steps:

[0026] (1) The chicken feathers are washed with water and dried, ground into powder by a pulverizer, and passed through a 800-mesh sieve;

[0027] (2) According to chicken feather powder: NaHSO 3 : [NEBM] BF 4 Mass ratio = 1:1:35 Mix the three to obtain a mixed solution, then add deionized water accounting for 20-30% of the total mass of the mixed solution, heat in a water bath at 80°C, stir for 1-3 hours, and collect the filtrate by hot filtration; Then add deionized water equivalent to 5 times the volume of the filtrate, centrifuge at a speed of 4000rpm for 10min, and collect chicken feather keratin; the filtrate is removed by rotary evaporation, and the morpholine ionic liquid and NaHSO are recovered 3 ;

[0028] (3) Take the chicken feather keratin obtained in the previou...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses chicken feather oligopeptide as well as an extraction method and application thereof, and relates to the technical field of daily cosmetics. A preparation method of the chicken feather oligopeptide comprises the following steps that (1) chicken feathers are crushed to obtain chicken feather powder; (2) the chicken feather powder, a reducing agent and morpholine ionic liquid are mixed uniformly, water is added, and stirring is achieved at 75-85 DEG C for 1-3 hours; filtrate is collected in a hot filtration manner; the water is added and centrifuging is achieved to obtain chicken feather keratin; and (3) keratinase is added into the chicken feather keratin, enzymolysis is performed at 37-50 DEG C for 8-12 hours, and enzyme deactivation is performed at 90-110 DEG C for 25-35 minutes; and the chicken feather oligopeptide with the molecular weight within 3000Da is separated from enzymatic hydrolysate by using an ultrafiltration membrane. The chicken feather oligopeptide prepared by the preparation method has good effects of activating hair follicles, improving a hair growth microenvironment and growing hair, can be externally applied to scalp, and has no side effect compared with oral medication.

Description

technical field [0001] The invention relates to the technical field of daily cosmetics, in particular to a chicken feather oligopeptide and its extraction method and application. Background technique [0002] In recent years, the clinical efficacy, mechanism of action and industrial application of bioactive peptides derived from animal and plant proteins have become a focus of attention and research at home and abroad. Many scientific research results have shown that these small molecule oligopeptides have the ability to enhance immunity, Various biological activities, such as improving the state of the body, regulating the intestinal flora, anti-oxidation and anti-aging, are loved by consumers and have great commercial development value and broad application prospects. At present, the production and consumption of broiler chickens are extremely large. However, a large amount of feather resources produced in the process of broiler chicken processing have not been fully utili...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12P21/06C07K14/465C07K1/14C07K1/34A61K8/64A61Q7/00
CPCC12P21/06C07K14/465C07K1/34A61K8/64A61Q7/00Y02P20/54
Inventor 闫昌誉余宗盛石飞严建刚李家炜萧玉媚栗原博古润金
Owner 广东完美生命健康科技研究院有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com