Moisturizing and soothing spray and preparation method thereof
A soothing and extractive technology, applied in the field of skin care products, can solve the problems of no long-term moisturizing effect, insufficient long-term moisturizing, and high cost of use, and achieves prolonged moisturizing effect, increased hydrophilicity, and good film-forming properties. Effect
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preparation example 1-4
[0047] Chitosan is selected from Shandong Changxiao Biological Engineering Co., Ltd., the article number is 101, and the molecular weight of PHB is 430000, and is selected from Tianjin Tianlu Co., Ltd.
preparation example 1
[0048] Preparation example 1: (1) 1kg chitosan is mixed with 5kg concentration of 42% sodium hydroxide solution, alkalized at 0°C for 24h, 40kg isopropanol is added, and 0.05kg chloroethanol is added dropwise under stirring, React at 75°C for 24h, dialyze with distilled water for 48h, and freeze-dry for 1h at a temperature of -20°C and a vacuum of 10Pa to obtain hydroxyethyl chitosan;
[0049] (2) Add 2 kg of hydroxyethyl chitosan to 3 kg of water, mix with 3 kg of 1% PHB in chloroform, add 0.05 kg of Span-80, seal and emulsify for 0.5 h, evaporate chloroform under reduced pressure, and wash with absolute ethanol , vacuum-dried to constant weight at 40°C and -0.1MPa to obtain PHB porous microspheres.
preparation example 2
[0050] Preparation example 2: (1) Mix 1.3kg chitosan with 6.5kg concentration of 45% sodium hydroxide solution, basify at 5°C for 20h, add 45kg isopropanol, and drop 0.08kg chlorine under stirring Ethanol, reacted at 80°C for 20h, dialyzed with distilled water for 50h, and freeze-dried for 1h at a temperature of -20°C and a vacuum of 10Pa to obtain hydroxyethyl chitosan;
[0051] (2) Add 3 kg of hydroxyethyl chitosan to 4 kg of water, mix with 4 kg of 2% PHB in chloroform, add 0.08 kg of Span-80, seal and emulsify for 0.8 h, evaporate chloroform under reduced pressure, and wash with absolute ethanol , vacuum-dried to constant weight at 40°C and -0.1MPa to obtain PHB porous microspheres.
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